Gastrointestinal cryptococcoma – Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?

The introduction of antiretroviral therapy (ART) may lead to unusual paradoxical and unmasking presentations of opportunistic infections. Intra-abdominal cryptococcosis is a rare manifestation of Cryptococcus. We present the case of an HIV-infected patient on ART, with a history of cryptococcal meni...

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Autores principales: Musubire, Abdu K., Meya, David B., Lukande, Robert, Kambugu, Andrew, Bohjanen, Paul R., Boulware, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389205/
https://www.ncbi.nlm.nih.gov/pubmed/25870787
http://dx.doi.org/10.1016/j.mmcr.2015.03.004
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author Musubire, Abdu K.
Meya, David B.
Lukande, Robert
Kambugu, Andrew
Bohjanen, Paul R.
Boulware, David R.
author_facet Musubire, Abdu K.
Meya, David B.
Lukande, Robert
Kambugu, Andrew
Bohjanen, Paul R.
Boulware, David R.
author_sort Musubire, Abdu K.
collection PubMed
description The introduction of antiretroviral therapy (ART) may lead to unusual paradoxical and unmasking presentations of opportunistic infections. Intra-abdominal cryptococcosis is a rare manifestation of Cryptococcus. We present the case of an HIV-infected patient on ART, with a history of cryptococcal meningitis who presented with subacute, worsening abdominal pain during immune recovery. This evolved into chronic abdominal pain, with thickened bowel, and abdominal lymphadenopathy, while receiving empiric tuberculosis treatment. At 6-months, he developed intestinal perforation due to a histologically confirmed cryptococcoma.
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spelling pubmed-43892052015-04-13 Gastrointestinal cryptococcoma – Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS? Musubire, Abdu K. Meya, David B. Lukande, Robert Kambugu, Andrew Bohjanen, Paul R. Boulware, David R. Med Mycol Case Rep Case Report The introduction of antiretroviral therapy (ART) may lead to unusual paradoxical and unmasking presentations of opportunistic infections. Intra-abdominal cryptococcosis is a rare manifestation of Cryptococcus. We present the case of an HIV-infected patient on ART, with a history of cryptococcal meningitis who presented with subacute, worsening abdominal pain during immune recovery. This evolved into chronic abdominal pain, with thickened bowel, and abdominal lymphadenopathy, while receiving empiric tuberculosis treatment. At 6-months, he developed intestinal perforation due to a histologically confirmed cryptococcoma. Elsevier 2015-03-26 /pmc/articles/PMC4389205/ /pubmed/25870787 http://dx.doi.org/10.1016/j.mmcr.2015.03.004 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Musubire, Abdu K.
Meya, David B.
Lukande, Robert
Kambugu, Andrew
Bohjanen, Paul R.
Boulware, David R.
Gastrointestinal cryptococcoma – Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?
title Gastrointestinal cryptococcoma – Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?
title_full Gastrointestinal cryptococcoma – Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?
title_fullStr Gastrointestinal cryptococcoma – Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?
title_full_unstemmed Gastrointestinal cryptococcoma – Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?
title_short Gastrointestinal cryptococcoma – Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?
title_sort gastrointestinal cryptococcoma – immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with aids?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389205/
https://www.ncbi.nlm.nih.gov/pubmed/25870787
http://dx.doi.org/10.1016/j.mmcr.2015.03.004
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