Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization

Here we show that iNOS-deficient mice display enhanced classically activated M1 macrophage polarization without major effects on alternatively activated M2 macrophages. eNOS and nNOS mutant mice show comparable M1 macrophage polarization compared with wild-type control mice. Addition of N6-(1-iminoe...

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Detalles Bibliográficos
Autores principales: Lu, Geming, Zhang, Ruihua, Geng, Shuo, Peng, Liang, Jayaraman, Padmini, Chen, Chun, Xu, Feifong, Yang, Jianjun, Li, Qin, Zheng, Hao, Shen, Kimberly, Wang, Juan, Liu, Xiyu, Wang, Weidong, Zheng, Zihan, Qi, Chen-Feng, Si, Chuanping, He, John Cijiang, Liu, Kebin, Lira, Sergio A., Sikora, Andrew G., Li, Liwu, Xiong, Huabao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389243/
https://www.ncbi.nlm.nih.gov/pubmed/25813085
http://dx.doi.org/10.1038/ncomms7676

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