Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains

Voltage-gated channels open paths for ion permeation upon changes in membrane potential, but how voltage changes are coupled to gating is not entirely understood. Two modules can be recognized in voltage-gated potassium channels, one responsible for voltage sensing (transmembrane segments S1 to S4),...

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Detalles Bibliográficos
Autores principales: Lörinczi, Éva, Gómez-Posada, Juan Camilo, de la Peña, Pilar, Tomczak, Adam P., Fernández-Trillo, Jorge, Leipscher, Ulrike, Stühmer, Walter, Barros, Francisco, Pardo, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389246/
https://www.ncbi.nlm.nih.gov/pubmed/25818916
http://dx.doi.org/10.1038/ncomms7672

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