Cargando…

Lagophthalmos and Frozen Globe as the Initial Presentation of Invasive Breast Carcinoma

A 75-year-old woman presented with six months history of progressing lagophthalmos and immobility of the left eye. Magnetic resonance imaging (MRI) of the orbit demonstrated infiltration of orbital fat and the extra-ocular muscles. We performed transverse blepharotomy of the left eyelid to correct l...

Descripción completa

Detalles Bibliográficos
Autores principales: Buttanri, Ibrahim Bulent, Akbaba, Muslime, Serin, Didem, Karslioglu, Safak, Ari, Seyhmus, Ozkara, Selvinaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical Hypothesis, Discovery & Innovation Ophthalmology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389293/
https://www.ncbi.nlm.nih.gov/pubmed/25861670
_version_ 1782365528199790592
author Buttanri, Ibrahim Bulent
Akbaba, Muslime
Serin, Didem
Karslioglu, Safak
Ari, Seyhmus
Ozkara, Selvinaz
author_facet Buttanri, Ibrahim Bulent
Akbaba, Muslime
Serin, Didem
Karslioglu, Safak
Ari, Seyhmus
Ozkara, Selvinaz
author_sort Buttanri, Ibrahim Bulent
collection PubMed
description A 75-year-old woman presented with six months history of progressing lagophthalmos and immobility of the left eye. Magnetic resonance imaging (MRI) of the orbit demonstrated infiltration of orbital fat and the extra-ocular muscles. We performed transverse blepharotomy of the left eyelid to correct lagophthalmos; and during surgery, we took a biopsy sample from levator muscle and orbital fat. After the operation, the patient was able to close her eyelids, and epithelial problems were resolved. Biopsy revealed fibro-vascular, muscle and fat tissue infiltrated with minimally differentiated carcinoma cells. Breast examination revealed a nodule in the left breast. Biopsy of the mass confirmed the diagnosis of invasive breast carcinoma. Orbital manifestation of metastases, such as diplopia, lagophthalmos or pain may reduce life quality of the patients and must be evaluated on a multidisciplinary basis.
format Online
Article
Text
id pubmed-4389293
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Medical Hypothesis, Discovery & Innovation Ophthalmology
record_format MEDLINE/PubMed
spelling pubmed-43892932015-04-08 Lagophthalmos and Frozen Globe as the Initial Presentation of Invasive Breast Carcinoma Buttanri, Ibrahim Bulent Akbaba, Muslime Serin, Didem Karslioglu, Safak Ari, Seyhmus Ozkara, Selvinaz Med Hypothesis Discov Innov Ophthalmol Case Report A 75-year-old woman presented with six months history of progressing lagophthalmos and immobility of the left eye. Magnetic resonance imaging (MRI) of the orbit demonstrated infiltration of orbital fat and the extra-ocular muscles. We performed transverse blepharotomy of the left eyelid to correct lagophthalmos; and during surgery, we took a biopsy sample from levator muscle and orbital fat. After the operation, the patient was able to close her eyelids, and epithelial problems were resolved. Biopsy revealed fibro-vascular, muscle and fat tissue infiltrated with minimally differentiated carcinoma cells. Breast examination revealed a nodule in the left breast. Biopsy of the mass confirmed the diagnosis of invasive breast carcinoma. Orbital manifestation of metastases, such as diplopia, lagophthalmos or pain may reduce life quality of the patients and must be evaluated on a multidisciplinary basis. Medical Hypothesis, Discovery & Innovation Ophthalmology 2015 /pmc/articles/PMC4389293/ /pubmed/25861670 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Buttanri, Ibrahim Bulent
Akbaba, Muslime
Serin, Didem
Karslioglu, Safak
Ari, Seyhmus
Ozkara, Selvinaz
Lagophthalmos and Frozen Globe as the Initial Presentation of Invasive Breast Carcinoma
title Lagophthalmos and Frozen Globe as the Initial Presentation of Invasive Breast Carcinoma
title_full Lagophthalmos and Frozen Globe as the Initial Presentation of Invasive Breast Carcinoma
title_fullStr Lagophthalmos and Frozen Globe as the Initial Presentation of Invasive Breast Carcinoma
title_full_unstemmed Lagophthalmos and Frozen Globe as the Initial Presentation of Invasive Breast Carcinoma
title_short Lagophthalmos and Frozen Globe as the Initial Presentation of Invasive Breast Carcinoma
title_sort lagophthalmos and frozen globe as the initial presentation of invasive breast carcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389293/
https://www.ncbi.nlm.nih.gov/pubmed/25861670
work_keys_str_mv AT buttanriibrahimbulent lagophthalmosandfrozenglobeastheinitialpresentationofinvasivebreastcarcinoma
AT akbabamuslime lagophthalmosandfrozenglobeastheinitialpresentationofinvasivebreastcarcinoma
AT serindidem lagophthalmosandfrozenglobeastheinitialpresentationofinvasivebreastcarcinoma
AT karslioglusafak lagophthalmosandfrozenglobeastheinitialpresentationofinvasivebreastcarcinoma
AT ariseyhmus lagophthalmosandfrozenglobeastheinitialpresentationofinvasivebreastcarcinoma
AT ozkaraselvinaz lagophthalmosandfrozenglobeastheinitialpresentationofinvasivebreastcarcinoma