Protective immunity against influenza H5N1 virus challenge in chickens by oral administration of recombinant Lactococcus lactis expressing neuraminidase

BACKGROUND: Highly pathogenic H5N1 avian influenza viruses pose a debilitating pandemic threat in poultry. Current influenza vaccines predominantly focus on hemagglutinin (HA) which anti-HA antibodies are often neutralizing, and are used routinely to assess vaccine immunogenicity. However, Neuramini...

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Detalles Bibliográficos
Autores principales: Lei, Han, Peng, Xiaojue, Ouyang, Jiexiu, Zhao, Daxian, Jiao, Huifeng, Shu, Handing, Ge, Xinqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389297/
https://www.ncbi.nlm.nih.gov/pubmed/25880824
http://dx.doi.org/10.1186/s12917-015-0399-4

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