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Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria

BACKGROUND: Sporozoite immunization of animals and humans under a chemo-prophylactic cover of chloroquine (CPS-CQ) efficiently induces sterile protection against malaria. In humans, CPS-CQ is strikingly more efficient than immunization with radiation attenuated sporozoites (RAS), raising the hypothe...

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Detalles Bibliográficos
Autores principales:	Bijker, Else M, Nganou-Makamdop, Krystelle, van Gemert, Geert-Jan, Zavala, Fidel, Cockburn, Ian, Sauerwein, Robert W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389414/ https://www.ncbi.nlm.nih.gov/pubmed/25889324 http://dx.doi.org/10.1186/s12936-015-0626-2

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