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Effects of an anti-inflammatory VAP-1/SSAO inhibitor, PXS-4728A, on pulmonary neutrophil migration

BACKGROUND AND PURPOSE: The persistent influx of neutrophils into the lung and subsequent tissue damage are characteristics of COPD, cystic fibrosis and acute lung inflammation. VAP-1/SSAO is an endothelial bound adhesion molecule with amine oxidase activity that is reported to be involved in neutro...

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Detalles Bibliográficos
Autores principales:	Schilter, Heidi C, Collison, Adam, Russo, Remo C, Foot, Jonathan S, Yow, Tin T, Vieira, Angelica T, Tavares, Livia D, Mattes, Joerg, Teixeira, Mauro M, Jarolimek, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389443/ https://www.ncbi.nlm.nih.gov/pubmed/25889951 http://dx.doi.org/10.1186/s12931-015-0200-z

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