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Improvement in cardioplegic perfusion technique in single aortic clamping - initial results
INTRODUCTION: The most common method used for myocardial protection is administering cardioplegic solution in the coronary circulation. Nevertheless, protection may be achieved by intermittent perfusion of the coronary system with patient's own blood. The intermittent perfusion may be performed...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Sociedade Brasileira de Cirurgia Cardiovascular
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389463/ https://www.ncbi.nlm.nih.gov/pubmed/25140473 http://dx.doi.org/10.5935/1678-9741.20140026 |
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author | Sobral, Marcelo Luiz Peixoto dos Santos Júnior, Sérgio Francisco de Sá, Juliano Cavalcante Terrazas, Anderson da Silva Trompieri, Daniel Francisco de Mendonça de Sousa, Thierry Araújo Nunes dos Santos, Gilmar Geraldo Stolf, Noedir Antonio Groppo |
author_facet | Sobral, Marcelo Luiz Peixoto dos Santos Júnior, Sérgio Francisco de Sá, Juliano Cavalcante Terrazas, Anderson da Silva Trompieri, Daniel Francisco de Mendonça de Sousa, Thierry Araújo Nunes dos Santos, Gilmar Geraldo Stolf, Noedir Antonio Groppo |
author_sort | Sobral, Marcelo Luiz Peixoto |
collection | PubMed |
description | INTRODUCTION: The most common method used for myocardial protection is administering cardioplegic solution in the coronary circulation. Nevertheless, protection may be achieved by intermittent perfusion of the coronary system with patient's own blood. The intermittent perfusion may be performed by multiple sequences of clamping and opening of the aortic clamp or due single clamping and accessory cannulation of the aortic root as in the improved technique proposed in this study, reperfusion without the need for multiple clamping of the aorta. OBJECTIVE: To evaluate the clinical outcome and the occurrence of neurological events in in-hospital patients submitted to myocardial revascularization surgery with the "improved technique" of intermittent perfusion of the aortic root with single clamping. METHODS: This is a prospective, cross-sectional, observational study that describes a myocardial management technique that consists of intermittent perfusion of the aortic root with single clamping in which 50 patients (mean age 58.5±7.19 years old) have been submitted to the myocardial revasculrization surgery under the proposed technique. Clinical and laboratory variables, pre- and post-surgery, have been assessed. RESULTS: The mean peak level of post-surgery CKMB was 51.64±27.10 U/L in the second post-surgery and of troponin I was 3.35±4.39 ng/ml in the fourth post-surgery, within normal limits. No deaths have occurred and one patient presented mild neurological disorder. Hemodynamic monitoring has not indicated any changes. CONCLUSION: The myocardial revascularization surgery by perfusion with the improved technique with intermittent aortic root with single clamping proved to be safe, enabling satisfactory clinical results. |
format | Online Article Text |
id | pubmed-4389463 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Sociedade Brasileira de Cirurgia Cardiovascular |
record_format | MEDLINE/PubMed |
spelling | pubmed-43894632015-04-14 Improvement in cardioplegic perfusion technique in single aortic clamping - initial results Sobral, Marcelo Luiz Peixoto dos Santos Júnior, Sérgio Francisco de Sá, Juliano Cavalcante Terrazas, Anderson da Silva Trompieri, Daniel Francisco de Mendonça de Sousa, Thierry Araújo Nunes dos Santos, Gilmar Geraldo Stolf, Noedir Antonio Groppo Rev Bras Cir Cardiovasc Original Articles INTRODUCTION: The most common method used for myocardial protection is administering cardioplegic solution in the coronary circulation. Nevertheless, protection may be achieved by intermittent perfusion of the coronary system with patient's own blood. The intermittent perfusion may be performed by multiple sequences of clamping and opening of the aortic clamp or due single clamping and accessory cannulation of the aortic root as in the improved technique proposed in this study, reperfusion without the need for multiple clamping of the aorta. OBJECTIVE: To evaluate the clinical outcome and the occurrence of neurological events in in-hospital patients submitted to myocardial revascularization surgery with the "improved technique" of intermittent perfusion of the aortic root with single clamping. METHODS: This is a prospective, cross-sectional, observational study that describes a myocardial management technique that consists of intermittent perfusion of the aortic root with single clamping in which 50 patients (mean age 58.5±7.19 years old) have been submitted to the myocardial revasculrization surgery under the proposed technique. Clinical and laboratory variables, pre- and post-surgery, have been assessed. RESULTS: The mean peak level of post-surgery CKMB was 51.64±27.10 U/L in the second post-surgery and of troponin I was 3.35±4.39 ng/ml in the fourth post-surgery, within normal limits. No deaths have occurred and one patient presented mild neurological disorder. Hemodynamic monitoring has not indicated any changes. CONCLUSION: The myocardial revascularization surgery by perfusion with the improved technique with intermittent aortic root with single clamping proved to be safe, enabling satisfactory clinical results. Sociedade Brasileira de Cirurgia Cardiovascular 2014 /pmc/articles/PMC4389463/ /pubmed/25140473 http://dx.doi.org/10.5935/1678-9741.20140026 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Sobral, Marcelo Luiz Peixoto dos Santos Júnior, Sérgio Francisco de Sá, Juliano Cavalcante Terrazas, Anderson da Silva Trompieri, Daniel Francisco de Mendonça de Sousa, Thierry Araújo Nunes dos Santos, Gilmar Geraldo Stolf, Noedir Antonio Groppo Improvement in cardioplegic perfusion technique in single aortic clamping - initial results |
title | Improvement in cardioplegic perfusion technique in single aortic clamping
- initial results |
title_full | Improvement in cardioplegic perfusion technique in single aortic clamping
- initial results |
title_fullStr | Improvement in cardioplegic perfusion technique in single aortic clamping
- initial results |
title_full_unstemmed | Improvement in cardioplegic perfusion technique in single aortic clamping
- initial results |
title_short | Improvement in cardioplegic perfusion technique in single aortic clamping
- initial results |
title_sort | improvement in cardioplegic perfusion technique in single aortic clamping
- initial results |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389463/ https://www.ncbi.nlm.nih.gov/pubmed/25140473 http://dx.doi.org/10.5935/1678-9741.20140026 |
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