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Improvement in cardioplegic perfusion technique in single aortic clamping - initial results

INTRODUCTION: The most common method used for myocardial protection is administering cardioplegic solution in the coronary circulation. Nevertheless, protection may be achieved by intermittent perfusion of the coronary system with patient's own blood. The intermittent perfusion may be performed...

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Autores principales: Sobral, Marcelo Luiz Peixoto, dos Santos Júnior, Sérgio Francisco, de Sá, Juliano Cavalcante, Terrazas, Anderson da Silva, Trompieri, Daniel Francisco de Mendonça, de Sousa, Thierry Araújo Nunes, dos Santos, Gilmar Geraldo, Stolf, Noedir Antonio Groppo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cirurgia Cardiovascular 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389463/
https://www.ncbi.nlm.nih.gov/pubmed/25140473
http://dx.doi.org/10.5935/1678-9741.20140026
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author Sobral, Marcelo Luiz Peixoto
dos Santos Júnior, Sérgio Francisco
de Sá, Juliano Cavalcante
Terrazas, Anderson da Silva
Trompieri, Daniel Francisco de Mendonça
de Sousa, Thierry Araújo Nunes
dos Santos, Gilmar Geraldo
Stolf, Noedir Antonio Groppo
author_facet Sobral, Marcelo Luiz Peixoto
dos Santos Júnior, Sérgio Francisco
de Sá, Juliano Cavalcante
Terrazas, Anderson da Silva
Trompieri, Daniel Francisco de Mendonça
de Sousa, Thierry Araújo Nunes
dos Santos, Gilmar Geraldo
Stolf, Noedir Antonio Groppo
author_sort Sobral, Marcelo Luiz Peixoto
collection PubMed
description INTRODUCTION: The most common method used for myocardial protection is administering cardioplegic solution in the coronary circulation. Nevertheless, protection may be achieved by intermittent perfusion of the coronary system with patient's own blood. The intermittent perfusion may be performed by multiple sequences of clamping and opening of the aortic clamp or due single clamping and accessory cannulation of the aortic root as in the improved technique proposed in this study, reperfusion without the need for multiple clamping of the aorta. OBJECTIVE: To evaluate the clinical outcome and the occurrence of neurological events in in-hospital patients submitted to myocardial revascularization surgery with the "improved technique" of intermittent perfusion of the aortic root with single clamping. METHODS: This is a prospective, cross-sectional, observational study that describes a myocardial management technique that consists of intermittent perfusion of the aortic root with single clamping in which 50 patients (mean age 58.5±7.19 years old) have been submitted to the myocardial revasculrization surgery under the proposed technique. Clinical and laboratory variables, pre- and post-surgery, have been assessed. RESULTS: The mean peak level of post-surgery CKMB was 51.64±27.10 U/L in the second post-surgery and of troponin I was 3.35±4.39 ng/ml in the fourth post-surgery, within normal limits. No deaths have occurred and one patient presented mild neurological disorder. Hemodynamic monitoring has not indicated any changes. CONCLUSION: The myocardial revascularization surgery by perfusion with the improved technique with intermittent aortic root with single clamping proved to be safe, enabling satisfactory clinical results.
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spelling pubmed-43894632015-04-14 Improvement in cardioplegic perfusion technique in single aortic clamping - initial results Sobral, Marcelo Luiz Peixoto dos Santos Júnior, Sérgio Francisco de Sá, Juliano Cavalcante Terrazas, Anderson da Silva Trompieri, Daniel Francisco de Mendonça de Sousa, Thierry Araújo Nunes dos Santos, Gilmar Geraldo Stolf, Noedir Antonio Groppo Rev Bras Cir Cardiovasc Original Articles INTRODUCTION: The most common method used for myocardial protection is administering cardioplegic solution in the coronary circulation. Nevertheless, protection may be achieved by intermittent perfusion of the coronary system with patient's own blood. The intermittent perfusion may be performed by multiple sequences of clamping and opening of the aortic clamp or due single clamping and accessory cannulation of the aortic root as in the improved technique proposed in this study, reperfusion without the need for multiple clamping of the aorta. OBJECTIVE: To evaluate the clinical outcome and the occurrence of neurological events in in-hospital patients submitted to myocardial revascularization surgery with the "improved technique" of intermittent perfusion of the aortic root with single clamping. METHODS: This is a prospective, cross-sectional, observational study that describes a myocardial management technique that consists of intermittent perfusion of the aortic root with single clamping in which 50 patients (mean age 58.5±7.19 years old) have been submitted to the myocardial revasculrization surgery under the proposed technique. Clinical and laboratory variables, pre- and post-surgery, have been assessed. RESULTS: The mean peak level of post-surgery CKMB was 51.64±27.10 U/L in the second post-surgery and of troponin I was 3.35±4.39 ng/ml in the fourth post-surgery, within normal limits. No deaths have occurred and one patient presented mild neurological disorder. Hemodynamic monitoring has not indicated any changes. CONCLUSION: The myocardial revascularization surgery by perfusion with the improved technique with intermittent aortic root with single clamping proved to be safe, enabling satisfactory clinical results. Sociedade Brasileira de Cirurgia Cardiovascular 2014 /pmc/articles/PMC4389463/ /pubmed/25140473 http://dx.doi.org/10.5935/1678-9741.20140026 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Sobral, Marcelo Luiz Peixoto
dos Santos Júnior, Sérgio Francisco
de Sá, Juliano Cavalcante
Terrazas, Anderson da Silva
Trompieri, Daniel Francisco de Mendonça
de Sousa, Thierry Araújo Nunes
dos Santos, Gilmar Geraldo
Stolf, Noedir Antonio Groppo
Improvement in cardioplegic perfusion technique in single aortic clamping - initial results
title Improvement in cardioplegic perfusion technique in single aortic clamping - initial results
title_full Improvement in cardioplegic perfusion technique in single aortic clamping - initial results
title_fullStr Improvement in cardioplegic perfusion technique in single aortic clamping - initial results
title_full_unstemmed Improvement in cardioplegic perfusion technique in single aortic clamping - initial results
title_short Improvement in cardioplegic perfusion technique in single aortic clamping - initial results
title_sort improvement in cardioplegic perfusion technique in single aortic clamping - initial results
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389463/
https://www.ncbi.nlm.nih.gov/pubmed/25140473
http://dx.doi.org/10.5935/1678-9741.20140026
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