The calcium paradox - What should we have to fear?

The calcium paradox was first mentioned in 1966 by Zimmerman et al. Thereafter gained great interest from the scientific community due to the fact of the absence of calcium ions in heart muscle cells produce damage similar to ischemia-reperfusion. Although not all known mechanisms involved in cellul...

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Autores principales: de Oliveira, Marcos Aurélio Barboza, Brandi, Antônio Carlos, dos Santos, Carlos Alberto, Botelho, Paulo Henrique Husseni, Cortez, José Luís Lasso, Goissis, Gilberto, Braile, Domingo Marcolino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cirurgia Cardiovascular 2014
Materias:
Special Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389471/
https://www.ncbi.nlm.nih.gov/pubmed/25140476
http://dx.doi.org/10.5935/1678-9741.20140054
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author de Oliveira, Marcos Aurélio Barboza
Brandi, Antônio Carlos
dos Santos, Carlos Alberto
Botelho, Paulo Henrique Husseni
Cortez, José Luís Lasso
Goissis, Gilberto
Braile, Domingo Marcolino
author_facet de Oliveira, Marcos Aurélio Barboza
Brandi, Antônio Carlos
dos Santos, Carlos Alberto
Botelho, Paulo Henrique Husseni
Cortez, José Luís Lasso
Goissis, Gilberto
Braile, Domingo Marcolino
author_sort de Oliveira, Marcos Aurélio Barboza
collection PubMed
description The calcium paradox was first mentioned in 1966 by Zimmerman et al. Thereafter gained great interest from the scientific community due to the fact of the absence of calcium ions in heart muscle cells produce damage similar to ischemia-reperfusion. Although not all known mechanisms involved in cellular injury in the calcium paradox intercellular connection maintained only by nexus seems to have a key role in cellular fragmentation. The addition of small concentrations of calcium, calcium channel blockers, and hyponatraemia hypothermia are important to prevent any cellular damage during reperfusion solutions with physiological concentration of calcium.
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spelling pubmed-43894712015-04-14 The calcium paradox - What should we have to fear? de Oliveira, Marcos Aurélio Barboza Brandi, Antônio Carlos dos Santos, Carlos Alberto Botelho, Paulo Henrique Husseni Cortez, José Luís Lasso Goissis, Gilberto Braile, Domingo Marcolino Rev Bras Cir Cardiovasc Special Articles The calcium paradox was first mentioned in 1966 by Zimmerman et al. Thereafter gained great interest from the scientific community due to the fact of the absence of calcium ions in heart muscle cells produce damage similar to ischemia-reperfusion. Although not all known mechanisms involved in cellular injury in the calcium paradox intercellular connection maintained only by nexus seems to have a key role in cellular fragmentation. The addition of small concentrations of calcium, calcium channel blockers, and hyponatraemia hypothermia are important to prevent any cellular damage during reperfusion solutions with physiological concentration of calcium. Sociedade Brasileira de Cirurgia Cardiovascular 2014 /pmc/articles/PMC4389471/ /pubmed/25140476 http://dx.doi.org/10.5935/1678-9741.20140054 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Articles
de Oliveira, Marcos Aurélio Barboza
Brandi, Antônio Carlos
dos Santos, Carlos Alberto
Botelho, Paulo Henrique Husseni
Cortez, José Luís Lasso
Goissis, Gilberto
Braile, Domingo Marcolino
The calcium paradox - What should we have to fear?
title The calcium paradox - What should we have to fear?
title_full The calcium paradox - What should we have to fear?
title_fullStr The calcium paradox - What should we have to fear?
title_full_unstemmed The calcium paradox - What should we have to fear?
title_short The calcium paradox - What should we have to fear?
title_sort calcium paradox - what should we have to fear?
topic Special Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389471/
https://www.ncbi.nlm.nih.gov/pubmed/25140476
http://dx.doi.org/10.5935/1678-9741.20140054
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