Zebrafish as a model for leukemia and other hematopoietic disorders

Zebrafish is an established model for the study of vertebrate development, and is especially amenable for investigating hematopoiesis, where there is strong conservation of key lineages, genes, and developmental processes with humans. Over recent years, zebrafish has been increasingly utilized as a...

Descripción completa

Detalles Bibliográficos
Autores principales: Rasighaemi, Parisa, Basheer, Faiza, Liongue, Clifford, Ward, Alister C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389495/
https://www.ncbi.nlm.nih.gov/pubmed/25884214
http://dx.doi.org/10.1186/s13045-015-0126-4
_version_ 1782365575313358848
author Rasighaemi, Parisa
Basheer, Faiza
Liongue, Clifford
Ward, Alister C
author_facet Rasighaemi, Parisa
Basheer, Faiza
Liongue, Clifford
Ward, Alister C
author_sort Rasighaemi, Parisa
collection PubMed
description Zebrafish is an established model for the study of vertebrate development, and is especially amenable for investigating hematopoiesis, where there is strong conservation of key lineages, genes, and developmental processes with humans. Over recent years, zebrafish has been increasingly utilized as a model for a range of human hematopoietic diseases, including malignancies. This review provides an overview of zebrafish hematopoiesis and describes its application as a model of leukemia and other hematopoietic disorders.
format Online
Article
Text
id pubmed-4389495
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-43894952015-04-09 Zebrafish as a model for leukemia and other hematopoietic disorders Rasighaemi, Parisa Basheer, Faiza Liongue, Clifford Ward, Alister C J Hematol Oncol Review Zebrafish is an established model for the study of vertebrate development, and is especially amenable for investigating hematopoiesis, where there is strong conservation of key lineages, genes, and developmental processes with humans. Over recent years, zebrafish has been increasingly utilized as a model for a range of human hematopoietic diseases, including malignancies. This review provides an overview of zebrafish hematopoiesis and describes its application as a model of leukemia and other hematopoietic disorders. BioMed Central 2015-03-28 /pmc/articles/PMC4389495/ /pubmed/25884214 http://dx.doi.org/10.1186/s13045-015-0126-4 Text en © Parisa et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Rasighaemi, Parisa
Basheer, Faiza
Liongue, Clifford
Ward, Alister C
Zebrafish as a model for leukemia and other hematopoietic disorders
title Zebrafish as a model for leukemia and other hematopoietic disorders
title_full Zebrafish as a model for leukemia and other hematopoietic disorders
title_fullStr Zebrafish as a model for leukemia and other hematopoietic disorders
title_full_unstemmed Zebrafish as a model for leukemia and other hematopoietic disorders
title_short Zebrafish as a model for leukemia and other hematopoietic disorders
title_sort zebrafish as a model for leukemia and other hematopoietic disorders
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389495/
https://www.ncbi.nlm.nih.gov/pubmed/25884214
http://dx.doi.org/10.1186/s13045-015-0126-4
work_keys_str_mv AT rasighaemiparisa zebrafishasamodelforleukemiaandotherhematopoieticdisorders
AT basheerfaiza zebrafishasamodelforleukemiaandotherhematopoieticdisorders
AT liongueclifford zebrafishasamodelforleukemiaandotherhematopoieticdisorders
AT wardalisterc zebrafishasamodelforleukemiaandotherhematopoieticdisorders

Ejemplares similares