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PCSK9 variation and association with blood pressure in African Americans: preliminary findings from the HyperGEN and REGARDS studies

Proprotein convertase subtilisin/kexin type 9 (encoded by PCSK9) plays a well-known role in the regulation of low-density lipoprotein (LDL) receptors, and an inhibitor of this enzyme is a promising new therapeutic for hyperlipidemia. Recently, animal and human studies also implicate PCSK9 genetic va...

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Detalles Bibliográficos
Autores principales:	Tran, Ngan T., Aslibekyan, Stella, Tiwari, Hemant K., Zhi, Degui, Sung, Yun Ju, Hunt, Steven C., Rao, DC, Broeckel, Ulrich, Judd, Suzanne E., Muntner, Paul, Kent, Shia T., Arnett, Donna K., Irvin, Marguerite R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389541/ https://www.ncbi.nlm.nih.gov/pubmed/25904937 http://dx.doi.org/10.3389/fgene.2015.00136

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