Use of the comet assay technique for quick and reliable prediction of in vitro response to chemotherapeutics in breast and colon cancer

BACKGROUND: Determination of response to chemotherapy is a major requirement of personalized medicine. Resistance, whether developed or native, critically affects a treatment’s success. Single Cell Gel lectrophoresis - also known as a comet assay - is used to detect DNA damage at the level of indivi...

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Detalles Bibliográficos
Autores principales: Apostolou, Panagiotis, Toloudi, Maria, Kourtidou, Eleni, Mimikakou, Georgia, Vlachou, Ioanna, Chatziioannou, Marina, Papasotiriou, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389674/
https://www.ncbi.nlm.nih.gov/pubmed/25984497
http://dx.doi.org/10.1186/2241-5793-21-14

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