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Multiplex bisulfite PCR resequencing of clinical FFPE DNA
BACKGROUND: The clinical utility of DNA methylation as a predictive or prognostic biomarker requires scalable resequencing protocols for bisulfite-converted DNA. Key features of any validation method should be adaptability for low- or high-throughput needs and high reproducibility, and should only r...
Autores principales: | Korbie, Darren, Lin, Erica, Wall, David, Nair, Shalima S, Stirzaker, Clare, Clark, Sue J, Trau, Matt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389706/ https://www.ncbi.nlm.nih.gov/pubmed/25861392 http://dx.doi.org/10.1186/s13148-015-0067-3 |
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