Shikonin selectively induces apoptosis in human prostate cancer cells through the endoplasmic reticulum stress and mitochondrial apoptotic pathway

BACKGROUND: Despite the recent progress in screening and therapy, a majority of prostate cancer cases eventually attain hormone refractory and chemo-resistant attributes. Conventional chemotherapeutic strategies are effective at very high doses for only palliative management of these prostate cancer...

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Detalles Bibliográficos
Autores principales: Gara, Rishi Kumar, Srivastava, Vikas Kumar, Duggal, Shivali, Bagga, Jaspreet Kaur, Bhatt, MLB, Sanyal, Sabyasachi, Mishra, Durga Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389804/
https://www.ncbi.nlm.nih.gov/pubmed/25879420
http://dx.doi.org/10.1186/s12929-015-0127-1

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