Cargando…

Combined ginger extract & Gelam honey modulate Ras/ERK and PI3K/AKT pathway genes in colon cancer HT29 cells

BACKGROUND: The interconnected Ras/ERK and PI3K/AKT pathways play a central role in colorectal tumorigenesis, and they are targets for elucidating mechanisms involved in attempts to induce colon cancer cell death. Both ginger (Zingiber officinale) and honey have been shown to exhibit anti-tumor and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tahir, Analhuda Abdullah, Sani, Nur Fathiah Abdul, Murad, Noor Azian, Makpol, Suzana, Ngah, Wan Zurinah Wan, Yusof, Yasmin Anum Mohd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390091/ https://www.ncbi.nlm.nih.gov/pubmed/25889965 http://dx.doi.org/10.1186/s12937-015-0015-2

Ejemplares similares

Effect of the Combination of Gelam Honey and Ginger on Oxidative Stress and Metabolic Profile in Streptozotocin-Induced Diabetic Sprague-Dawley Rats
por: Abdul Sani, Nur Fathiah, et al.
Publicado: (2014)

Gelam Honey Attenuates Carrageenan-Induced Rat Paw Inflammation via NF-κB Pathway
por: Hussein, Saba Zuhair, et al.
Publicado: (2013)

Gelam Honey Protects against Gamma-Irradiation Damage to Antioxidant Enzymes in Human Diploid Fibroblasts
por: Ahmad, Tengku Ahbrizal Farizal Tengku, et al.
Publicado: (2013)

Gelam Honey Inhibits the Production of Proinflammatory, Mediators NO, PGE(2), TNF-α, and IL-6 in Carrageenan-Induced Acute Paw Edema in Rats
por: Hussein, Saba Zuhair, et al.
Publicado: (2012)

Ginger Extract (Zingiber Officinale) has Anti-Cancer and Anti-Inflammatory Effects on Ethionine-Induced Hepatoma Rats
por: Habib, Shafina Hanim Mohd, et al.
Publicado: (2008)

γ-Tocotrienol and 6-Gingerol in Combination Synergistically Induce Cytotoxicity and Apoptosis in HT-29 and SW837 Human Colorectal Cancer Cells
por: Md Yusof, Khairunnisa’, et al.
Publicado: (2015)

Modulation of collagen synthesis and its gene expression in human skin fibroblasts by tocotrienol-rich fraction
por: Makpol, Suzana, et al.
Publicado: (2011)

Gene Expression Profile in Different Age Groups and Its Association with Cognitive Function in Healthy Malay Adults in Malaysia
por: Abdul Sani, Nur Fathiah, et al.
Publicado: (2021)

Gamma-tocotrienol modulation of senescence-associated gene expression prevents cellular aging in human diploid fibroblasts
por: Makpol, Suzana, et al.
Publicado: (2012)

Gamma-Tocotrienol Modulated Gene Expression in Senescent Human Diploid Fibroblasts as Revealed by Microarray Analysis
por: Makpol, Suzana, et al.
Publicado: (2013)

Gelam honey potentiates ex vivo corneal keratocytes proliferation with desirable phenotype expression
por: Yusof, Alia Md, et al.
Publicado: (2016)

Piper betle induces phase I & II genes through Nrf2/ARE signaling pathway in mouse embryonic fibroblasts derived from wild type and Nrf2 knockout cells
por: Wan Hasan, Wan Nuraini, et al.
Publicado: (2014)

Tocotrienol-Rich Fraction Prevents Cell Cycle Arrest and Elongates Telomere Length in Senescent Human Diploid Fibroblasts
por: Makpol, Suzana, et al.
Publicado: (2011)

Hot water extract of Chlorella vulgaris induced DNA damage and apoptosis
por: Yusof, Yasmin Anum Mohd, et al.
Publicado: (2010)

Vitamin E in Sarcopenia: Current Evidences on Its Role in Prevention and Treatment
por: Khor, Shy Cian, et al.
Publicado: (2014)

Tocotrienol-Rich Fraction Ameliorates Antioxidant Defense Mechanisms and Improves Replicative Senescence-Associated Oxidative Stress in Human Myoblasts
por: Khor, Shy Cian, et al.
Publicado: (2017)

Combinatorial Cytotoxic Effects of Gelam Honey and 5-Fluorouracil against Human Adenocarcinoma Colon Cancer HT-29 Cells In Vitro
por: T-Johari, Syed Ahmad Tajudin, et al.
Publicado: (2019)

Antioxidant enzyme activity and malondialdehyde levels can be modulated by Piper betle, tocotrienol rich fraction and Chlorella vulgaris in aging C57BL/6 mice
por: Aliahmat, Nor Syahida, et al.
Publicado: (2012)

Comparative Effects of Biodynes, Tocotrienol-Rich Fraction, and Tocopherol in Enhancing Collagen Synthesis and Inhibiting Collagen Degradation in Stress-Induced Premature Senescence Model of Human Diploid Fibroblasts
por: Makpol, Suzana, et al.
Publicado: (2013)

Corrigendum to “Combinatorial Cytotoxic Effects of Gelam Honey and 5-Fluorouracil against Human Adenocarcinoma Colon Cancer HT-29 Cells In Vitro”
por: T-Johari, Syed Ahmad Tajudin, et al.
Publicado: (2019)

The Tocotrienol-Rich Fraction Is Superior to Tocopherol in Promoting Myogenic Differentiation in the Prevention of Replicative Senescence of Myoblasts
por: Khor, Shy Cian, et al.
Publicado: (2016)

The effects of acacia honey on in vitro corneal abrasion wound healing model
por: Ker-Woon, Choy, et al.
Publicado: (2015)

Acacia honey accelerates in vitro corneal ulcer wound healing model
por: Abd Ghafar, Norzana, et al.
Publicado: (2016)

Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study
por: Chin, Siok-Fong, et al.
Publicado: (2011)

Comparative Effects of Alpha- and Gamma-Tocopherol on Mitochondrial Functions in Alzheimer’s Disease In Vitro Model
por: Pahrudin Arrozi, Aslina, et al.
Publicado: (2020)

Gelam honey attenuated radiation-induced cell death in human diploid fibroblasts by promoting cell cycle progression and inhibiting apoptosis
por: Tengku Ahmad, Tengku Ahbrizal Farizal, et al.
Publicado: (2014)

Gelam (Melaleuca spp.) Honey-Based Hydrogel as Burn Wound Dressing
por: Mohd Zohdi, Rozaini, et al.
Publicado: (2012)

Antioxidant Capacities and Total Phenolic Contents Increase with Gamma Irradiation in Two Types of Malaysian Honey
por: Hussein, Saba Zuhair, et al.
Publicado: (2011)

Gelam Honey Scavenges Peroxynitrite During the Immune Response
por: Kassim, Mustafa, et al.
Publicado: (2012)

Gelam Honey Attenuates the Oxidative Stress-Induced Inflammatory Pathways in Pancreatic Hamster Cells
por: Safi, Sher Zaman, et al.
Publicado: (2016)

Inhibition of Mitochondrial Cytochrome c Release and Suppression of Caspases by Gamma-Tocotrienol Prevent Apoptosis and Delay Aging in Stress-Induced Premature Senescence of Skin Fibroblasts
por: Makpol, Suzana, et al.
Publicado: (2012)

Modulatory Effects of Alpha- and Gamma-Tocopherol on the Mitochondrial Respiratory Capacity and Membrane Potential in an In Vitro Model of Alzheimer’s Disease
por: Pahrudin Arrozi, Aslina, et al.
Publicado: (2021)

Effect of Gelam Honey on the Oxidative Stress-Induced Signaling Pathways in Pancreatic Hamster Cells
por: Batumalaie, Kalaivani, et al.
Publicado: (2013)

Effects of Gelam and Acacia honey acute administration on some biochemical parameters of Sprague Dawley rats
por: Samat, Suhana, et al.
Publicado: (2014)

The Efficacy of Gelam Honey Dressing towards Excisional Wound Healing
por: Tan, Mui Koon, et al.
Publicado: (2012)

Modulation of vulvovaginal atrophy (VVA) by Gelam honey in bilateral oophorectomized rats
por: Ismail, Nur Hilwani, et al.
Publicado: (2023)

Tocotrienol-Rich Fraction, [6]-Gingerol and Epigallocatechin Gallate Inhibit Proliferation and Induce Apoptosis of Glioma Cancer Cells
por: Rahman, Amirah Abdul, et al.
Publicado: (2014)

Inhibitory Mechanism of Combined Hydroxychavicol With Epigallocatechin-3-Gallate Against Glioma Cancer Cell Lines: A Transcriptomic Analysis
por: Abdul Rahman, Amirah, et al.
Publicado: (2022)

Tocotrienol Rich Fraction Supplementation Modulate Brain Hippocampal Gene Expression in APPswe/PS1dE9 Alzheimer’s Disease Mouse Model
por: Wan Nasri, Wan Nurzulaikha, et al.
Publicado: (2019)

High sPLA2-IIA level is associated with eicosanoid metabolism in patients with bacterial sepsis syndrome
por: Ahmad, Nurul Saadah, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vjjctg8rlrdb8b888nkcimpbg3