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Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: Evolving role of TonEBP

Degeneration of the intervertebral disc is characterized by changes in proteoglycan status, loss of bound water molecules, decreased tissue osmotic pressure and a resulting mechanical failure of the disc. A similar spectrum of changes is evident in osteoarthritic articular cartilage. When healthy, r...

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Detalles Bibliográficos
Autores principales:	Johnson, Zariel I., Shapiro, Irving M., Risbud, Makarand V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390124/ https://www.ncbi.nlm.nih.gov/pubmed/25172826 http://dx.doi.org/10.1016/j.matbio.2014.08.014

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