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Mass Spectrometric Quantification of Histone Post-translational Modifications by a Hybrid Chemical Labeling Method
Mass spectrometry is a powerful alternative to antibody-based methods for the analysis of histone post-translational modifications (marks). A key development in this approach was the deliberate propionylation of histones to improve sequence coverage across the lysine-rich and hydrophilic tails that...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390259/ https://www.ncbi.nlm.nih.gov/pubmed/25680960 http://dx.doi.org/10.1074/mcp.O114.046573 |