Rectal Application of a Highly Osmolar Personal Lubricant in a Macaque Model Induces Acute Cytotoxicity but Does Not Increase Risk of SHIV Infection

BACKGROUND: Personal lubricant use is common during anal intercourse. Some water-based products with high osmolality and low pH can damage genital and rectal tissues, and the polymer polyquaternium 15 (PQ15) can enhance HIV replication in vitro. This has raised concerns that lubricants with such pro...

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Detalles Bibliográficos
Autores principales: Vishwanathan, Sundaram A., Morris, Monica R., Wolitski, Richard J., Luo, Wei, Rose, Charles E., Blau, Dianna M., Tsegaye, Theodros, Zaki, Sherif R., Garber, David A., Jenkins, Leecresia T., Henning, Tara C., Patton, Dorothy L., Hendry, R. Michael, McNicholl, Janet M., Kersh, Ellen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390343/
https://www.ncbi.nlm.nih.gov/pubmed/25853710
http://dx.doi.org/10.1371/journal.pone.0120021

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