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Functional Genomics Screening Utilizing Mutant Mouse Embryonic Stem Cells Identifies Novel Radiation-Response Genes

Elucidating the genetic determinants of radiation response is crucial to optimizing and individualizing radiotherapy for cancer patients. In order to identify genes that are involved in enhanced sensitivity or resistance to radiation, a library of stable mutant murine embryonic stem cells (ESCs), ea...

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Detalles Bibliográficos
Autores principales:	Loesch, Kimberly, Galaviz, Stacy, Hamoui, Zaher, Clanton, Ryan, Akabani, Gamal, Deveau, Michael, DeJesus, Michael, Ioerger, Thomas, Sacchettini, James C., Wallis, Deeann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390347/ https://www.ncbi.nlm.nih.gov/pubmed/25853515 http://dx.doi.org/10.1371/journal.pone.0120534

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