Inducible in vivo genome editing with CRISPR/Cas9

CRISPR/Cas9-based genome editing enables the rapid genetic manipulation of any genomic locus without the need for gene targeting by homologous recombination. Here we describe a conditional transgenic approach that allows temporal control of CRISPR/Cas9 activity for inducible genome editing in adult...

Descripción completa

Detalles Bibliográficos
Autores principales: Dow, Lukas E, Fisher, Jonathan, O'Rourke, Kevin P, Muley, Ashlesha, Kastenhuber, Edward R, Livshits, Geulah, Tschaharganeh, Darjus F, Socci, Nicholas D, Lowe, Scott W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390466/
https://www.ncbi.nlm.nih.gov/pubmed/25690852
http://dx.doi.org/10.1038/nbt.3155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390466/
https://www.ncbi.nlm.nih.gov/pubmed/25690852
http://dx.doi.org/10.1038/nbt.3155

Ejemplares similares