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I’m Positive, But I’m Negative: Competing Voices in Informed Consent and Implications for HIV Vaccine Trials
HIV vaccine trials (HVTs) are ethically complex, and sound informed consent processes should facilitate optimal decision-making for participants. This study aimed to explore representations of critical HVT-related concepts to enhance the consent process. Four focus group discussions were conducted w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390555/ https://www.ncbi.nlm.nih.gov/pubmed/25819758 http://dx.doi.org/10.1177/1556264615575509 |
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author | Rautenbach, Clinton Lindegger, Graham Slack, Catherine Wallace, Melissa Newman, Peter |
author_facet | Rautenbach, Clinton Lindegger, Graham Slack, Catherine Wallace, Melissa Newman, Peter |
author_sort | Rautenbach, Clinton |
collection | PubMed |
description | HIV vaccine trials (HVTs) are ethically complex, and sound informed consent processes should facilitate optimal decision-making for participants. This study aimed to explore representations of critical HVT-related concepts to enhance the consent process. Four focus group discussions were conducted with participants from key constituencies at a South African HVT site. Thematic analysis was employed to identify representations of key HVT-related concepts. The findings suggest that (potential) participants may negotiate multiple, competing versions of HVT-related concepts in a somewhat unrecognized process, which may have significant implications for the consent process. Stakeholders involved in consent and engagement activities at sites should be assisted to elicit, engage, and resolve competing representations of HVT-related concepts. More empirical research is needed to explore how such stakeholders address competing representations in their interactions with potential participants. |
format | Online Article Text |
id | pubmed-4390555 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-43905552015-05-15 I’m Positive, But I’m Negative: Competing Voices in Informed Consent and Implications for HIV Vaccine Trials Rautenbach, Clinton Lindegger, Graham Slack, Catherine Wallace, Melissa Newman, Peter J Empir Res Hum Res Ethics Informed Consent HIV vaccine trials (HVTs) are ethically complex, and sound informed consent processes should facilitate optimal decision-making for participants. This study aimed to explore representations of critical HVT-related concepts to enhance the consent process. Four focus group discussions were conducted with participants from key constituencies at a South African HVT site. Thematic analysis was employed to identify representations of key HVT-related concepts. The findings suggest that (potential) participants may negotiate multiple, competing versions of HVT-related concepts in a somewhat unrecognized process, which may have significant implications for the consent process. Stakeholders involved in consent and engagement activities at sites should be assisted to elicit, engage, and resolve competing representations of HVT-related concepts. More empirical research is needed to explore how such stakeholders address competing representations in their interactions with potential participants. SAGE Publications 2015-04 /pmc/articles/PMC4390555/ /pubmed/25819758 http://dx.doi.org/10.1177/1556264615575509 Text en © The Author(s) 2015 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (http://www.uk.sagepub.com/aboutus/openaccess.htm). |
spellingShingle | Informed Consent Rautenbach, Clinton Lindegger, Graham Slack, Catherine Wallace, Melissa Newman, Peter I’m Positive, But I’m Negative: Competing Voices in Informed Consent and Implications for HIV Vaccine Trials |
title | I’m Positive, But I’m Negative: Competing Voices in Informed Consent and Implications for HIV Vaccine Trials |
title_full | I’m Positive, But I’m Negative: Competing Voices in Informed Consent and Implications for HIV Vaccine Trials |
title_fullStr | I’m Positive, But I’m Negative: Competing Voices in Informed Consent and Implications for HIV Vaccine Trials |
title_full_unstemmed | I’m Positive, But I’m Negative: Competing Voices in Informed Consent and Implications for HIV Vaccine Trials |
title_short | I’m Positive, But I’m Negative: Competing Voices in Informed Consent and Implications for HIV Vaccine Trials |
title_sort | i’m positive, but i’m negative: competing voices in informed consent and implications for hiv vaccine trials |
topic | Informed Consent |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390555/ https://www.ncbi.nlm.nih.gov/pubmed/25819758 http://dx.doi.org/10.1177/1556264615575509 |
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