Incidences and Prognostic Impact of c-KIT, WT1, CEBPA, and CBL Mutations, and Mutations Associated With Epigenetic Modification in Core Binding Factor Acute Myeloid Leukemia: A Multicenter Study in a Korean Population

BACKGROUND: To identify potential molecular prognostic markers in core binding factor (CBF) AML, we analyzed incidences and prognostic impacts of mutations in c-KIT, WT1, CEBPA, CBL, and a number of epigenetic genes in CBF AML. METHODS: Seventy one and 21 AML patients with t(8;21) and inv(16) were e...

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Detalles Bibliográficos
Autores principales: Park, Sang Hyuk, Lee, Hyun Ji, Kim, In-Suk, Kang, Jeong-Eun, Lee, Eun Yup, Kim, Hyeoung-Joon, Kim, Yeo-Kyeoung, Won, Jong-Ho, Bang, Soo Mee, Kim, Hawk, Song, Moo-Kon, Chung, Joo Seop, Shin, Ho-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Laboratory Medicine 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390696/
https://www.ncbi.nlm.nih.gov/pubmed/25932436
http://dx.doi.org/10.3343/alm.2015.35.3.288

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