Bestrophin-1 influences transepithelial electrical properties and Ca(2+) signaling in human retinal pigment epithelium

PURPOSE: Mutations in BEST1, encoding Bestrophin-1 (Best1), cause Best vitelliform macular dystrophy (BVMD) and other inherited retinal degenerative diseases. Best1 is an integral membrane protein localized to the basolateral plasma membrane of the retinal pigment epithelium (RPE). Data from numerou...

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Detalles Bibliográficos
Autores principales: Marmorstein, Alan D., Kinnick, Tyson R., Stanton, J. Brett, Johnson, Adiv A., Lynch, Ronald M., Marmorstein, Lihua Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390793/
https://www.ncbi.nlm.nih.gov/pubmed/25878489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390793/
https://www.ncbi.nlm.nih.gov/pubmed/25878489

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