From Formamide to RNA, the Path Is Tenuous but Continuous

Reactions of formamide (NH(2)COH) in the presence of catalysts of both terrestrial and meteoritic origin yield, in plausible and variegated conditions, a large panel of precursors of (pre)genetic and (pre)metabolic interest. Formamide chemistry potentially satisfies all of the steps from the very in...

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Autores principales: Pino, Samanta, Sponer, Judit E., Costanzo, Giovanna, Saladino, Raffaele, Di Mauro, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390857/
https://www.ncbi.nlm.nih.gov/pubmed/25647486
http://dx.doi.org/10.3390/life5010372
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author Pino, Samanta
Sponer, Judit E.
Costanzo, Giovanna
Saladino, Raffaele
Di Mauro, Ernesto
author_facet Pino, Samanta
Sponer, Judit E.
Costanzo, Giovanna
Saladino, Raffaele
Di Mauro, Ernesto
author_sort Pino, Samanta
collection PubMed
description Reactions of formamide (NH(2)COH) in the presence of catalysts of both terrestrial and meteoritic origin yield, in plausible and variegated conditions, a large panel of precursors of (pre)genetic and (pre)metabolic interest. Formamide chemistry potentially satisfies all of the steps from the very initial precursors to RNA. Water chemistry enters the scene in RNA non-enzymatic synthesis and recombination.
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spelling pubmed-43908572015-05-21 From Formamide to RNA, the Path Is Tenuous but Continuous Pino, Samanta Sponer, Judit E. Costanzo, Giovanna Saladino, Raffaele Di Mauro, Ernesto Life (Basel) Article Reactions of formamide (NH(2)COH) in the presence of catalysts of both terrestrial and meteoritic origin yield, in plausible and variegated conditions, a large panel of precursors of (pre)genetic and (pre)metabolic interest. Formamide chemistry potentially satisfies all of the steps from the very initial precursors to RNA. Water chemistry enters the scene in RNA non-enzymatic synthesis and recombination. MDPI 2015-01-30 /pmc/articles/PMC4390857/ /pubmed/25647486 http://dx.doi.org/10.3390/life5010372 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pino, Samanta
Sponer, Judit E.
Costanzo, Giovanna
Saladino, Raffaele
Di Mauro, Ernesto
From Formamide to RNA, the Path Is Tenuous but Continuous
title From Formamide to RNA, the Path Is Tenuous but Continuous
title_full From Formamide to RNA, the Path Is Tenuous but Continuous
title_fullStr From Formamide to RNA, the Path Is Tenuous but Continuous
title_full_unstemmed From Formamide to RNA, the Path Is Tenuous but Continuous
title_short From Formamide to RNA, the Path Is Tenuous but Continuous
title_sort from formamide to rna, the path is tenuous but continuous
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390857/
https://www.ncbi.nlm.nih.gov/pubmed/25647486
http://dx.doi.org/10.3390/life5010372
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