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Structural dynamics of myosin 5 during processive motion revealed by interferometric scattering microscopy

Myosin 5a is a dual-headed molecular motor that transports cargo along actin filaments. By following the motion of individual heads with interferometric scattering microscopy at nm spatial and ms temporal precision we found that the detached head occupies a loosely fixed position to one side of acti...

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Detalles Bibliográficos
Autores principales:	Andrecka, Joanna, Ortega Arroyo, Jaime, Takagi, Yasuharu, de Wit, Gabrielle, Fineberg, Adam, MacKinnon, Lachlan, Young, Gavin, Sellers, James R, Kukura, Philipp
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391024/ https://www.ncbi.nlm.nih.gov/pubmed/25748137 http://dx.doi.org/10.7554/eLife.05413

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