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The 'Switch’ study protocol: a randomised-controlled trial of switching to an alternative tumour-necrosis factor (TNF)-inhibitor drug or abatacept or rituximab in patients with rheumatoid arthritis who have failed an initial TNF-inhibitor drug
BACKGROUND: Rheumatoid Arthritis (RA) is one of the most common autoimmune diseases, affecting approximately 1% of the UK adult population. Patients suffer considerable pain, stiffness and swelling and can sustain various degrees of joint destruction, deformity, and significant functional decline. I...
Autores principales: | Navarro Coy, Nuria C, Brown, Sarah, Bosworth, Ailsa, Davies, Claire T, Emery, Paul, Everett, Colin C, Fernandez, Catherine, Gray, Janine C, Hartley, Suzanne, Hulme, Claire, Keenan, Anne-Maree, McCabe, Christopher, Redmond, Anthony, Reynolds, Catherine, Scott, David, Sharples, Linda D, Pavitt, Sue, Buch, Maya H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391115/ https://www.ncbi.nlm.nih.gov/pubmed/25539805 http://dx.doi.org/10.1186/1471-2474-15-452 |
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