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Leucine alters hepatic glucose/lipid homeostasis via the myostatin-AMP-activated protein kinase pathway - potential implications for nonalcoholic fatty liver disease

BACKGROUND: Elevated plasma levels of the branched-chain amino acid (BCAA) leucine are associated with obesity and insulin resistance (IR), and thus the propensity for type 2 diabetes mellitus development. However, other clinical studies suggest the contradictory view that leucine may in fact offer...

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Detalles Bibliográficos
Autores principales:	Zarfeshani, Aida, Ngo, Sherry, Sheppard, Allan M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391119/ https://www.ncbi.nlm.nih.gov/pubmed/25859286 http://dx.doi.org/10.1186/1868-7083-6-27

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