Genome-wide methylation profiling of the different stages of hepatitis B virus-related hepatocellular carcinoma development in plasma cell-free DNA reveals potential biomarkers for early detection and high-risk monitoring of hepatocellular carcinoma

BACKGROUND: An important model of hepatocellular carcinoma (HCC) that has been described in southeast Asia includes the transition from chronic hepatitis B infection (CHB) to liver cirrhosis (LC) and, finally, to HCC. The genome-wide methylation profiling of plasma cell-free DNA (cfDNA) has not prev...

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Detalles Bibliográficos
Autores principales: Zhao, Yangxing, Xue, Feng, Sun, Jinfeng, Guo, Shicheng, Zhang, Hongyu, Qiu, Bijun, Geng, Junfeng, Gu, Jun, Zhou, Xiaoyu, Wang, Wei, Zhang, Zhenfeng, Tang, Ning, He, Yinghua, Yu, Jian, Xia, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391300/
https://www.ncbi.nlm.nih.gov/pubmed/25859288
http://dx.doi.org/10.1186/1868-7083-6-30

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