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Use of benzodiazepines and detoxification with methadone

Rationale: Benzodiazepines are used as anti anxiety drugs, as well as in adjunct treatment for a range of neurological and psychiatric disorders. Abusive patterns of use were increasingly reported and building evidence points to prevalence of benzodiazepines abuse, on one hand as well as to their co...

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Autores principales: Popescu, G, Negrei, C, Bălălău, D, Ciobanu, AM, Baconi, D, Bălălău, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391402/
https://www.ncbi.nlm.nih.gov/pubmed/25870711
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author Popescu, G
Negrei, C
Bălălău, D
Ciobanu, AM
Baconi, D
Bălălău, C
author_facet Popescu, G
Negrei, C
Bălălău, D
Ciobanu, AM
Baconi, D
Bălălău, C
author_sort Popescu, G
collection PubMed
description Rationale: Benzodiazepines are used as anti anxiety drugs, as well as in adjunct treatment for a range of neurological and psychiatric disorders. Abusive patterns of use were increasingly reported and building evidence points to prevalence of benzodiazepines abuse, on one hand as well as to their common abuse in combination with other drugs such as opioids, most frequently. Objective: The main objective of this research is to conduct a systematic study on the behavior profile of a patient admitted to a prison hospital, who is a benzodiazepines user consecutive to admission into a methadone administration program. Methods and results: Statistic values have been taken into account describing the distribution and the distribution form of the various variables studied to find the normality degree of distributions, regarding three measurements at the three moments: before the administration of methadone, immediately after its completion and two months after completion. Conclusions and discussions: The statistic results obtained speak of a strong positive correlation, allowing the support of the fact that persons diagnosed with prescribed/ unprescribed benzodiazepine, use the display association with the admission into a methadone administration program, based on the assumption which concerns a significant positive association between the use of reported benzodiazepine and the administration of methadone in the questioned patients on admission. As far as the second premise regarding the administration of methadone is concerned it brings about an improvement in the level of benzodiazepines used in research patients, which one may assert that, according to the results obtained, the initiation of methadone therapy in the detoxification program is conducive to the reduction of benzodiazepines use.
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spelling pubmed-43914022015-04-13 Use of benzodiazepines and detoxification with methadone Popescu, G Negrei, C Bălălău, D Ciobanu, AM Baconi, D Bălălău, C J Med Life Young Researchers Area Rationale: Benzodiazepines are used as anti anxiety drugs, as well as in adjunct treatment for a range of neurological and psychiatric disorders. Abusive patterns of use were increasingly reported and building evidence points to prevalence of benzodiazepines abuse, on one hand as well as to their common abuse in combination with other drugs such as opioids, most frequently. Objective: The main objective of this research is to conduct a systematic study on the behavior profile of a patient admitted to a prison hospital, who is a benzodiazepines user consecutive to admission into a methadone administration program. Methods and results: Statistic values have been taken into account describing the distribution and the distribution form of the various variables studied to find the normality degree of distributions, regarding three measurements at the three moments: before the administration of methadone, immediately after its completion and two months after completion. Conclusions and discussions: The statistic results obtained speak of a strong positive correlation, allowing the support of the fact that persons diagnosed with prescribed/ unprescribed benzodiazepine, use the display association with the admission into a methadone administration program, based on the assumption which concerns a significant positive association between the use of reported benzodiazepine and the administration of methadone in the questioned patients on admission. As far as the second premise regarding the administration of methadone is concerned it brings about an improvement in the level of benzodiazepines used in research patients, which one may assert that, according to the results obtained, the initiation of methadone therapy in the detoxification program is conducive to the reduction of benzodiazepines use. Carol Davila University Press 2014 /pmc/articles/PMC4391402/ /pubmed/25870711 Text en ©Carol Davila University Press http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Young Researchers Area
Popescu, G
Negrei, C
Bălălău, D
Ciobanu, AM
Baconi, D
Bălălău, C
Use of benzodiazepines and detoxification with methadone
title Use of benzodiazepines and detoxification with methadone
title_full Use of benzodiazepines and detoxification with methadone
title_fullStr Use of benzodiazepines and detoxification with methadone
title_full_unstemmed Use of benzodiazepines and detoxification with methadone
title_short Use of benzodiazepines and detoxification with methadone
title_sort use of benzodiazepines and detoxification with methadone
topic Young Researchers Area
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391402/
https://www.ncbi.nlm.nih.gov/pubmed/25870711
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