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Assessment of acid-base balance at birth in newborns from diabetic mothers
Newborns from diabetic mothers are more frequently born prematurely, large for the gestational age, with difficult respiratory adaptation and risk of RDS (respiratory distress syndrome) and, subsequently, exposed to a higher risk of perinatal distress, hypoxia, metabolic stress and hematologic alter...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Carol Davila University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391410/ https://www.ncbi.nlm.nih.gov/pubmed/25870703 |
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author | Stanescu, A Stoicescu, SM |
author_facet | Stanescu, A Stoicescu, SM |
author_sort | Stanescu, A |
collection | PubMed |
description | Newborns from diabetic mothers are more frequently born prematurely, large for the gestational age, with difficult respiratory adaptation and risk of RDS (respiratory distress syndrome) and, subsequently, exposed to a higher risk of perinatal distress, hypoxia, metabolic stress and hematologic alterations. Comparing the status at birth of 120 newborns from mothers with diabetes, with 120 controls from uncomplicated pregnancies, over a period of 4 years, in a specialized tertiary center, no significant differences in the immediate outcome of such newborns and similar incidence of hypoxia at birth were shown, as illustrated by the parameters of the acid-base balance (cord pH, BE and HCO3). However, there are significant differences in the route of delivery, with a predominance of C-section deliveries in the diabetic group (4 out of every 5 cases), which might be an important contribution to the relative good status of these newborns at birth. Although balanced at birth, the newborns from diabetic mothers need intensive monitoring and care in the subsequent hours after birth, for important risks such as hypoglycemic episodes. |
format | Online Article Text |
id | pubmed-4391410 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Carol Davila University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-43914102015-04-13 Assessment of acid-base balance at birth in newborns from diabetic mothers Stanescu, A Stoicescu, SM J Med Life Case Presentations Newborns from diabetic mothers are more frequently born prematurely, large for the gestational age, with difficult respiratory adaptation and risk of RDS (respiratory distress syndrome) and, subsequently, exposed to a higher risk of perinatal distress, hypoxia, metabolic stress and hematologic alterations. Comparing the status at birth of 120 newborns from mothers with diabetes, with 120 controls from uncomplicated pregnancies, over a period of 4 years, in a specialized tertiary center, no significant differences in the immediate outcome of such newborns and similar incidence of hypoxia at birth were shown, as illustrated by the parameters of the acid-base balance (cord pH, BE and HCO3). However, there are significant differences in the route of delivery, with a predominance of C-section deliveries in the diabetic group (4 out of every 5 cases), which might be an important contribution to the relative good status of these newborns at birth. Although balanced at birth, the newborns from diabetic mothers need intensive monitoring and care in the subsequent hours after birth, for important risks such as hypoglycemic episodes. Carol Davila University Press 2014 /pmc/articles/PMC4391410/ /pubmed/25870703 Text en ©Carol Davila University Press http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Presentations Stanescu, A Stoicescu, SM Assessment of acid-base balance at birth in newborns from diabetic mothers |
title | Assessment of acid-base balance at birth in newborns
from diabetic mothers
|
title_full | Assessment of acid-base balance at birth in newborns
from diabetic mothers
|
title_fullStr | Assessment of acid-base balance at birth in newborns
from diabetic mothers
|
title_full_unstemmed | Assessment of acid-base balance at birth in newborns
from diabetic mothers
|
title_short | Assessment of acid-base balance at birth in newborns
from diabetic mothers
|
title_sort | assessment of acid-base balance at birth in newborns
from diabetic mothers |
topic | Case Presentations |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391410/ https://www.ncbi.nlm.nih.gov/pubmed/25870703 |
work_keys_str_mv | AT stanescua assessmentofacidbasebalanceatbirthinnewbornsfromdiabeticmothers AT stoicescusm assessmentofacidbasebalanceatbirthinnewbornsfromdiabeticmothers |