Clinical significance of HPV-DNA testing for precancerous cervical lesionS

Cervical screening by using cytology was proven efficient in reducing the mortality secondary to cervical cancer, but this method has limitations. High risk HPV infection is essential for cervical cancer development so HPV testing is a new tool used for screening patients for cervical neoplasia. HPV...

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Autores principales: Moarcăs, M, Georgescu, IC, Brătilă, E, Badea, M, Cîrstoiu, ECM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2014
Materias:
General Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391422/
https://www.ncbi.nlm.nih.gov/pubmed/25870692
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author Moarcăs, M
Georgescu, IC
Brătilă, E
Badea, M
Cîrstoiu, ECM
author_facet Moarcăs, M
Georgescu, IC
Brătilă, E
Badea, M
Cîrstoiu, ECM
author_sort Moarcăs, M
collection PubMed
description Cervical screening by using cytology was proven efficient in reducing the mortality secondary to cervical cancer, but this method has limitations. High risk HPV infection is essential for cervical cancer development so HPV testing is a new tool used for screening patients for cervical neoplasia. HPV testing was proven most useful for women over 30 years old, in cases in which cytology identified ASC-US and after treatment for CIN. This article outlines the clinical significance of HPV-DNA testing for precancerous cervical lesions and the evidence that stands behind these recommendations. Abbreviations: HPV = Human Papilloma Virus, ASC-US = Atypical Squamous Cells of Undetermined Significance, CIN = Cervical Intraepithelial Neoplasia, LSIL = Low Grade Squamous Intraepithelial Lesion, DNA = Deoxyribonucleic Acid
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spelling pubmed-43914222015-04-13 Clinical significance of HPV-DNA testing for precancerous cervical lesionS Moarcăs, M Georgescu, IC Brătilă, E Badea, M Cîrstoiu, ECM J Med Life General Articles Cervical screening by using cytology was proven efficient in reducing the mortality secondary to cervical cancer, but this method has limitations. High risk HPV infection is essential for cervical cancer development so HPV testing is a new tool used for screening patients for cervical neoplasia. HPV testing was proven most useful for women over 30 years old, in cases in which cytology identified ASC-US and after treatment for CIN. This article outlines the clinical significance of HPV-DNA testing for precancerous cervical lesions and the evidence that stands behind these recommendations. Abbreviations: HPV = Human Papilloma Virus, ASC-US = Atypical Squamous Cells of Undetermined Significance, CIN = Cervical Intraepithelial Neoplasia, LSIL = Low Grade Squamous Intraepithelial Lesion, DNA = Deoxyribonucleic Acid Carol Davila University Press 2014 /pmc/articles/PMC4391422/ /pubmed/25870692 Text en ©Carol Davila University Press http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle General Articles
Moarcăs, M
Georgescu, IC
Brătilă, E
Badea, M
Cîrstoiu, ECM
Clinical significance of HPV-DNA testing for precancerous cervical lesionS
title Clinical significance of HPV-DNA testing for precancerous cervical lesionS
title_full Clinical significance of HPV-DNA testing for precancerous cervical lesionS
title_fullStr Clinical significance of HPV-DNA testing for precancerous cervical lesionS
title_full_unstemmed Clinical significance of HPV-DNA testing for precancerous cervical lesionS
title_short Clinical significance of HPV-DNA testing for precancerous cervical lesionS
title_sort clinical significance of hpv-dna testing for precancerous cervical lesions
topic General Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391422/
https://www.ncbi.nlm.nih.gov/pubmed/25870692
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