Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcome

BACKGROUND: DNA hypermethylation is reported as a frequent event and prognostic marker in head and neck squamous cell carcinomas (HNSCC). Methylation has been commonly assessed with non-quantitative methodologies, such as methylation-specific PCR (MSP). We investigated previously reported hypermethy...

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Detalles Bibliográficos
Autores principales: Lim, Annette M, Candiloro, Ida LM, Wong, Nicholas, Collins, Marnie, Do, Hongdo, Takano, Elena A, Angel, Christopher, Young, Richard J, Corry, June, Wiesenfeld, David, Kleid, Stephen, Sigston, Elizabeth, Lyons, Bernard, Rischin, Danny, Solomon, Benjamin, Dobrovic, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391486/
https://www.ncbi.nlm.nih.gov/pubmed/25859283
http://dx.doi.org/10.1186/1868-7083-6-22

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