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Non-targeted metabolomics and lipidomics LC–MS data from maternal plasma of 180 healthy pregnant women

BACKGROUND: Metabolomics has the potential to be a powerful and sensitive approach for investigating the low molecular weight metabolite profiles present in maternal fluids and their role in pregnancy. FINDINGS: In this Data Note, LC–MS metabolome, lipidome and carnitine profiling data were collecte...

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Autores principales: Luan, Hemi, Meng, Nan, Liu, Ping, Fu, Jin, Chen, Xiaomin, Rao, Weiqiao, Jiang, Hui, Xu, Xun, Cai, Zongwei, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391677/
https://www.ncbi.nlm.nih.gov/pubmed/25859341
http://dx.doi.org/10.1186/s13742-015-0054-9
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author Luan, Hemi
Meng, Nan
Liu, Ping
Fu, Jin
Chen, Xiaomin
Rao, Weiqiao
Jiang, Hui
Xu, Xun
Cai, Zongwei
Wang, Jun
author_facet Luan, Hemi
Meng, Nan
Liu, Ping
Fu, Jin
Chen, Xiaomin
Rao, Weiqiao
Jiang, Hui
Xu, Xun
Cai, Zongwei
Wang, Jun
author_sort Luan, Hemi
collection PubMed
description BACKGROUND: Metabolomics has the potential to be a powerful and sensitive approach for investigating the low molecular weight metabolite profiles present in maternal fluids and their role in pregnancy. FINDINGS: In this Data Note, LC–MS metabolome, lipidome and carnitine profiling data were collected from 180 healthy pregnant women, representing six time points spanning all three trimesters, and providing sufficient coverage to model the progression of normal pregnancy. CONCLUSIONS: As a relatively large scale, real-world dataset with robust numbers of quality control samples, the data are expected to prove useful for algorithm optimization and development, with the potential to augment studies into abnormal pregnancy. All data and ISA-TAB format enriched metadata are available for download in the MetaboLights and GigaScience databases. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13742-015-0054-9) contains supplementary material, which is available to authorized users.
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spelling pubmed-43916772015-04-10 Non-targeted metabolomics and lipidomics LC–MS data from maternal plasma of 180 healthy pregnant women Luan, Hemi Meng, Nan Liu, Ping Fu, Jin Chen, Xiaomin Rao, Weiqiao Jiang, Hui Xu, Xun Cai, Zongwei Wang, Jun Gigascience Data Note BACKGROUND: Metabolomics has the potential to be a powerful and sensitive approach for investigating the low molecular weight metabolite profiles present in maternal fluids and their role in pregnancy. FINDINGS: In this Data Note, LC–MS metabolome, lipidome and carnitine profiling data were collected from 180 healthy pregnant women, representing six time points spanning all three trimesters, and providing sufficient coverage to model the progression of normal pregnancy. CONCLUSIONS: As a relatively large scale, real-world dataset with robust numbers of quality control samples, the data are expected to prove useful for algorithm optimization and development, with the potential to augment studies into abnormal pregnancy. All data and ISA-TAB format enriched metadata are available for download in the MetaboLights and GigaScience databases. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13742-015-0054-9) contains supplementary material, which is available to authorized users. BioMed Central 2015-04-09 /pmc/articles/PMC4391677/ /pubmed/25859341 http://dx.doi.org/10.1186/s13742-015-0054-9 Text en © Luan et al.; licensee BioMed Central. 2015 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Data Note
Luan, Hemi
Meng, Nan
Liu, Ping
Fu, Jin
Chen, Xiaomin
Rao, Weiqiao
Jiang, Hui
Xu, Xun
Cai, Zongwei
Wang, Jun
Non-targeted metabolomics and lipidomics LC–MS data from maternal plasma of 180 healthy pregnant women
title Non-targeted metabolomics and lipidomics LC–MS data from maternal plasma of 180 healthy pregnant women
title_full Non-targeted metabolomics and lipidomics LC–MS data from maternal plasma of 180 healthy pregnant women
title_fullStr Non-targeted metabolomics and lipidomics LC–MS data from maternal plasma of 180 healthy pregnant women
title_full_unstemmed Non-targeted metabolomics and lipidomics LC–MS data from maternal plasma of 180 healthy pregnant women
title_short Non-targeted metabolomics and lipidomics LC–MS data from maternal plasma of 180 healthy pregnant women
title_sort non-targeted metabolomics and lipidomics lc–ms data from maternal plasma of 180 healthy pregnant women
topic Data Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391677/
https://www.ncbi.nlm.nih.gov/pubmed/25859341
http://dx.doi.org/10.1186/s13742-015-0054-9
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