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Direct confirmation of quiescence of CD34+CD38- leukemia stem cell populations using single cell culture, their molecular signature and clinicopathological implications

BACKGROUND: The proliferating activity of a single leukemia stem cell and the molecular mechanisms for their quiescent property remain unknown, and also their prognostic value remains a matter of debate. Therefore, this study aimed to demonstrate the quiescence property and molecular signature of le...

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Detalles Bibliográficos
Autores principales:	Won, Eun Jeong, Kim, Hye-Ran, Park, Ra-Young, Choi, Seok-Yong, Shin, Jong Hee, Suh, Soon-Pal, Ryang, Dong-Wook, Szardenings, Michael, Shin, Myung-Geun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391681/ https://www.ncbi.nlm.nih.gov/pubmed/25881148 http://dx.doi.org/10.1186/s12885-015-1233-x

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