Cargando…

Direct confirmation of quiescence of CD34+CD38- leukemia stem cell populations using single cell culture, their molecular signature and clinicopathological implications

BACKGROUND: The proliferating activity of a single leukemia stem cell and the molecular mechanisms for their quiescent property remain unknown, and also their prognostic value remains a matter of debate. Therefore, this study aimed to demonstrate the quiescence property and molecular signature of le...

Descripción completa

Detalles Bibliográficos
Autores principales:	Won, Eun Jeong, Kim, Hye-Ran, Park, Ra-Young, Choi, Seok-Yong, Shin, Jong Hee, Suh, Soon-Pal, Ryang, Dong-Wook, Szardenings, Michael, Shin, Myung-Geun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391681/ https://www.ncbi.nlm.nih.gov/pubmed/25881148 http://dx.doi.org/10.1186/s12885-015-1233-x

Ejemplares similares

Phenotyping and Target Expression Profiling of CD34(+)/CD38(−) and CD34(+)/CD38(+) Stem- and Progenitor cells in Acute Lymphoblastic Leukemia
por: Blatt, Katharina, et al.
Publicado: (2018)

Genomic and Proteomic Analysis of the Impact of Mitotic Quiescence on the Engraftment of Human CD34(+) Cells
por: Chitteti, Brahmananda Reddy, et al.
Publicado: (2011)

Quiescence, Stemness and Adipogenic Differentiation Capacity in Human DLK1(−)/CD34(+)/CD24(+) Adipose Stem/Progenitor Cells
por: Hatzmann, Florian M., et al.
Publicado: (2021)

Mitochondrial DNA Aberrations of Bone Marrow Cells from Patients with Aplastic Anemia
por: Kim, Hye-Ran, et al.
Publicado: (2008)

Interferon gamma selectively inhibits very primitive CD342+CD38- and not more mature CD34+CD38+ human hematopoietic progenitor cells
Publicado: (1994)

A molecular signature of dormancy in CD34(+)CD38(-) acute myeloid leukaemia cells
por: Al-Asadi, Mazin Gh., et al.
Publicado: (2017)

CD45(dim)CD34(+)CD38(−)CD133(+) cells have the potential as leukemic stem cells in acute myeloid leukemia
por: Heo, Sook-Kyoung, et al.
Publicado: (2020)

Effect of DLK1 on tumorigenesis in CD34(+)CD38(−) bone marrow cells in myelodysplastic syndromes
por: ZHANG, WEI, et al.
Publicado: (2013)

CD34 and CD38 are prognostic biomarkers for acute B lymphoblastic leukemia
por: Jiang, Zhiwu, et al.
Publicado: (2016)

Clinicopathological Implications of Mitochondrial Genome Alterations in Pediatric Acute Myeloid Leukemia
por: Kang, Min-Gu, et al.
Publicado: (2016)

Seroepidemiology of Toxocariasis and Its Clinical Implications in Gwangju and Jeonnam-province, Korea
por: Won, Eun Jeong, et al.
Publicado: (2015)

Immunoprofiling of leukemic stem cells CD34+/CD38−/CD123+ delineate FLT3/ITD-positive clones
por: Al-Mawali, Adhra, et al.
Publicado: (2016)

Survival outcomes of CD34(+)CD38(−)LSCs and their expression of CD123 in adult AML patients
por: Zahran, Asmaa M., et al.
Publicado: (2018)

CD150(high) CD4 T cells and CD150(high) regulatory T cells regulate hematopoietic stem cell quiescence via CD73
por: Hirata, Yuichi, et al.
Publicado: (2019)

Wnt1 Accelerates an Ex Vivo Expansion of Human Cord Blood CD34(+)CD38(−) Cells
por: Chotinantakul, Kamonnaree, et al.
Publicado: (2013)

Heterogeneity of CD34 and CD38 expression in acute B lymphoblastic leukemia cells is reversible and not hierarchically organized
por: Jiang, Zhiwu, et al.
Publicado: (2016)

CD34+/CD38- Stem Cell Burden Could Predict Chronic Myeloid Leukemia Patients’ Outcome
por: Fathy El-Metwaly, Noura, et al.
Publicado: (2021)

Molecular Identification of Schizophyllum commune as a Cause of Allergic Fungal Sinusitis
por: Won, Eun Jeong, et al.
Publicado: (2012)

Evaluation of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry-Based VITEK MS System for the Identification of Acinetobacter Species from Blood Cultures: Comparison with VITEK 2 and MicroScan Systems
por: Lee, Seung Yeob, et al.
Publicado: (2015)

Clinicopathological features of superficial CD34-positive fibroblastic tumor
por: Ding, Li, et al.
Publicado: (2021)

Spectra of Chromosomal Aberrations in 325 Leukemia Patients and Implications for the Development of New Molecular Detection Systems
por: Choi, Hyun-Jung, et al.
Publicado: (2011)

Nilotinib Enhances the Efficacy of Conventional Chemotherapeutic Drugs in CD34(+)CD38(−) Stem Cells and ABC Transporter Overexpressing Leukemia Cells
por: Wang, Fang, et al.
Publicado: (2014)

Multilocus Sequence Typing for Candida albicans Isolates from Candidemic Patients: Comparison with Southern Blot Hybridization and Pulsed-field Gel Electrophoresis Analysis
por: Myoung, Youn, et al.
Publicado: (2011)

Allelic Expression Imbalance of JAK2 V617F Mutation in BCR-ABL Negative Myeloproliferative Neoplasms
por: Kim, Hye-Ran, et al.
Publicado: (2013)

The number of CD34+CD38+CD117+HLA-DR+CD13+CD33+ cells indicates post-chemotherapy hematopoietic recovery in patients with acute myeloid leukemia
por: Gu, Runxia, et al.
Publicado: (2017)

Targeting of CD34(+)CD38(-) cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in acute Myeloid Leukaemia
por: Jawad, Mays, et al.
Publicado: (2012)

Proteomic Profiling Identifies Distinct Protein Patterns in Acute Myelogenous Leukemia CD34+CD38- Stem-Like Cells
por: Kornblau, Steven M., et al.
Publicado: (2013)

High frequency of CD34+CD38-/low immature leukemia cells is correlated with unfavorable prognosis in acute myeloid leukemia
por: Plesa, Adriana, et al.
Publicado: (2017)

Prospective validation of the prognostic relevance of CD34(+)CD38(–) AML stem cell frequency in the HOVON-SAKK132 trial
por: Ngai, Lok Lam, et al.
Publicado: (2023)

Behavior and Functional Roles of CD34(+) Mesenchymal Cells in Mammalian Testes
por: Abe, Shin-ichi
Publicado: (2022)

Plasma proGRP Concentration is Sensitive and Specific for Discriminating Small Cell Lung Cancer from Nonmalignant Conditions or Non-small Cell Lung Cancer
por: Kim, Hye-Ran, et al.
Publicado: (2011)

Alteration of the SETBP1 Gene and Splicing Pathway Genes SF3B1, U2AF1, and SRSF2 in Childhood Acute Myeloid Leukemia
por: Choi, Hyun-Woo, et al.
Publicado: (2015)

Coexistence of JAK2 and CALR mutations and their clinical implications in patients with essential thrombocythemia
por: Kang, Min-Gu, et al.
Publicado: (2016)

Differential cytokine effects on primitive (CD34+CD38-) human hematopoietic cells: novel responses to Flt3-ligand and thrombopoietin
Publicado: (1996)

FISH(+)CD34(+)CD38(-) cells detected in newly diagnosed acute myeloid leukemia patients can predict the clinical outcome
por: Wang, Libing, et al.
Publicado: (2013)

HIV-1 infection depletes human CD34(+)CD38(-) hematopoietic progenitor cells via pDC-dependent mechanisms
por: Li, Guangming, et al.
Publicado: (2017)

A new way to maintain CD8(+) T-cell quiescence: interaction between CD8α and PILRα
por: Jin, Ke, et al.
Publicado: (2022)

Reduced Cellular Susceptibility to In Vitro HIV Infection Is Associated with CD4+ T Cell Quiescence
por: Card, Catherine M., et al.
Publicado: (2012)

The clinicopathological features of ganglioglioma with CD34 expression and BRAF mutation in patients with epilepsy
por: Xie, Ming-Guo, et al.
Publicado: (2023)

Differential number of CD34+, CD133+ and CD34+/CD133+ cells in peripheral blood of patients with congestive heart failure
por: Fritzenwanger, M, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_hn5udd1nvm5mjga2pmpbh12srm