LINE-1 hypomethylation is neither present in rectal aberrant crypt foci nor associated with field defect in sporadic colorectal neoplasia

BACKGROUND: Aberrant crypt foci (ACF) are considered the first identifiable preneoplastic lesion in colorectal cancer (CRC), and have been proposed as a potential biomarker for CRC risk. Global DNA hypomethylation is an early event in colorectal carcinogenesis, and long interspersed nuclear element-...

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Detalles Bibliográficos
Autores principales: Quintanilla, Isabel, Lopez-Cerón, Maria, Jimeno, Mireya, Cuatrecasas, Miriam, Muñoz, Jennifer, Moreira, Leticia, Carballal, Sabela, Leoz, Maria Liz, Camps, Jordi, Castells, Antoni, Pellisé, Maria, Balaguer, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391726/
https://www.ncbi.nlm.nih.gov/pubmed/25859284
http://dx.doi.org/10.1186/1868-7083-6-24

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