Opposing Activity Changes in AMP Deaminase and AMP-Activated Protein Kinase in the Hibernating Ground Squirrel

Hibernating animals develop fatty liver when active in summertime and undergo a switch to a fat oxidation state in the winter. We hypothesized that this switch might be determined by AMP and the dominance of opposing effects: metabolism through AMP deaminase (AMPD2) (summer) and activation of AMP-ac...

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Detalles Bibliográficos
Autores principales: Lanaspa, Miguel A., Epperson, L. Elaine, Li, Nanxing, Cicerchi, Christina, Garcia, Gabriela E., Roncal-Jimenez, Carlos A., Trostel, Jessica, Jain, Swati, Mant, Colin T., Rivard, Christopher J., Ishimoto, Takuji, Shimada, Michiko, Sanchez-Lozada, Laura Gabriela, Nakagawa, Takahiko, Jani, Alkesh, Stenvinkel, Peter, Martin, Sandra L., Johnson, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391924/
https://www.ncbi.nlm.nih.gov/pubmed/25856396
http://dx.doi.org/10.1371/journal.pone.0123509

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