Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo

Caspase-2 is an atypical caspase that regulates apoptosis, cell cycle arrest and genome maintenance, although the mechanisms are not well understood. Caspase-2 has also been implicated in chemotherapy response in lung cancer, but this function has not been addressed in vivo. Here we show that Caspas...

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Detalles Bibliográficos
Autores principales: Terry, M R, Arya, R, Mukhopadhyay, A, Berrett, K C, Clair, P M, Witt, B, Salama, M E, Bhutkar, A, Oliver, T G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392070/
https://www.ncbi.nlm.nih.gov/pubmed/25301067
http://dx.doi.org/10.1038/cdd.2014.159

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