Metformin-Clinical Pharmacology in PCOs

Oligo-anovulation, hyperandrogenism and insulin resistance characterizes polycystic ovary syndrome (PCOs). Metformin is the oldest insulin sensitizer used in the management of type 2 diabetes mellitus. In PCOs, metformin decreases the serum lipids, androgen and insulin; induces ovulation and regular...

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Detalles Bibliográficos
Autores principales: Dumitrescu, R, Mehedintu, C, Briceag, I, Purcărea, VL, Hudita, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2015
Materias:
General Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392089/
https://www.ncbi.nlm.nih.gov/pubmed/25866577
Descripción
Sumario:Oligo-anovulation, hyperandrogenism and insulin resistance characterizes polycystic ovary syndrome (PCOs). Metformin is the oldest insulin sensitizer used in the management of type 2 diabetes mellitus. In PCOs, metformin decreases the serum lipids, androgen and insulin; induces ovulation and regular menstrual cycle; increases the pregnancy rate.

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