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Controversies in the diagnosis and treatment of early cutaneous melanoma

Cutaneous melanoma (CM) is a disease with an unpredictable evolution mainly due to its high metastatic ability. The steadily increasing incidence and the poor outcome in advanced stages made this cancer an interesting field for many research groups. Given that CM is a curable disease in early stages...

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Detalles Bibliográficos
Autores principales: Orzan, OA, Șandru, A, Jecan, CR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392104/
https://www.ncbi.nlm.nih.gov/pubmed/25866567
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author Orzan, OA
Șandru, A
Jecan, CR
author_facet Orzan, OA
Șandru, A
Jecan, CR
author_sort Orzan, OA
collection PubMed
description Cutaneous melanoma (CM) is a disease with an unpredictable evolution mainly due to its high metastatic ability. The steadily increasing incidence and the poor outcome in advanced stages made this cancer an interesting field for many research groups. Given that CM is a curable disease in early stages, efforts have been made to detect it as soon as possible, which led to the diversification and refining of diagnosis methods and therapies. But, as the data from trials have been published, doubts about the indications and efficacy of established treatments have arisen. In fact, there is probably no single aspect of early CM that has not given birth to controversy. This article intends to present the current disputes regarding the early detection, diagnosis, treatment and postoperative follow-up of patients with localized CM. After analyzing both pros and cons, several conclusions were drawn, that reflect our experience in managing patients with early CM.
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spelling pubmed-43921042015-06-01 Controversies in the diagnosis and treatment of early cutaneous melanoma Orzan, OA Șandru, A Jecan, CR J Med Life Reviews Cutaneous melanoma (CM) is a disease with an unpredictable evolution mainly due to its high metastatic ability. The steadily increasing incidence and the poor outcome in advanced stages made this cancer an interesting field for many research groups. Given that CM is a curable disease in early stages, efforts have been made to detect it as soon as possible, which led to the diversification and refining of diagnosis methods and therapies. But, as the data from trials have been published, doubts about the indications and efficacy of established treatments have arisen. In fact, there is probably no single aspect of early CM that has not given birth to controversy. This article intends to present the current disputes regarding the early detection, diagnosis, treatment and postoperative follow-up of patients with localized CM. After analyzing both pros and cons, several conclusions were drawn, that reflect our experience in managing patients with early CM. Carol Davila University Press 2015 /pmc/articles/PMC4392104/ /pubmed/25866567 Text en ©Carol Davila University Press http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Orzan, OA
Șandru, A
Jecan, CR
Controversies in the diagnosis and treatment of early cutaneous melanoma
title Controversies in the diagnosis and treatment of early cutaneous melanoma
title_full Controversies in the diagnosis and treatment of early cutaneous melanoma
title_fullStr Controversies in the diagnosis and treatment of early cutaneous melanoma
title_full_unstemmed Controversies in the diagnosis and treatment of early cutaneous melanoma
title_short Controversies in the diagnosis and treatment of early cutaneous melanoma
title_sort controversies in the diagnosis and treatment of early cutaneous melanoma
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392104/
https://www.ncbi.nlm.nih.gov/pubmed/25866567
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