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Performances of a portable electrospinning apparatus

To demonstrate that portable electrospinning devices can spin a wide range of polymers into submicron fibres and provide a mesh quality comparable to those produced with benchtop machines. We have designed a small, battery-operated electrospinning apparatus which enables control over the voltage and...

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Autores principales: Mouthuy, Pierre-Alexis, Groszkowski, Lukasz, Ye, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392120/
https://www.ncbi.nlm.nih.gov/pubmed/25549609
http://dx.doi.org/10.1007/s10529-014-1760-6
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author Mouthuy, Pierre-Alexis
Groszkowski, Lukasz
Ye, Hua
author_facet Mouthuy, Pierre-Alexis
Groszkowski, Lukasz
Ye, Hua
author_sort Mouthuy, Pierre-Alexis
collection PubMed
description To demonstrate that portable electrospinning devices can spin a wide range of polymers into submicron fibres and provide a mesh quality comparable to those produced with benchtop machines. We have designed a small, battery-operated electrospinning apparatus which enables control over the voltage and the flow rate of the polymer solution via a microcontroller. It can be used to electrospin a range of commonly used polymers including poly(ε-caprolactone), poly(p-dioxanone), poly(lactic-co-glycolic acid), poly(3-hydroxybutyrate), poly(ethylene oxide), poly(vinyl acohol) and poly(vinyl butyral). Moreover, electrospun meshes are produced with a quality comparable to a benchtop machine. We also show that the portable apparatus is able to electrospray beads and microparticles. Finally, we highlight the potential of the device for wound healing applications by demonstrating the possibility of electrospinning onto pig and human skins. Portable electrospinning devices are still at an early stage of development but they could soon become an attractive alternative to benchtop machines, in particular for uses that require mobility and a higher degree of flexibility, such as for wound healing applications.
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spelling pubmed-43921202015-04-13 Performances of a portable electrospinning apparatus Mouthuy, Pierre-Alexis Groszkowski, Lukasz Ye, Hua Biotechnol Lett Original Research Paper To demonstrate that portable electrospinning devices can spin a wide range of polymers into submicron fibres and provide a mesh quality comparable to those produced with benchtop machines. We have designed a small, battery-operated electrospinning apparatus which enables control over the voltage and the flow rate of the polymer solution via a microcontroller. It can be used to electrospin a range of commonly used polymers including poly(ε-caprolactone), poly(p-dioxanone), poly(lactic-co-glycolic acid), poly(3-hydroxybutyrate), poly(ethylene oxide), poly(vinyl acohol) and poly(vinyl butyral). Moreover, electrospun meshes are produced with a quality comparable to a benchtop machine. We also show that the portable apparatus is able to electrospray beads and microparticles. Finally, we highlight the potential of the device for wound healing applications by demonstrating the possibility of electrospinning onto pig and human skins. Portable electrospinning devices are still at an early stage of development but they could soon become an attractive alternative to benchtop machines, in particular for uses that require mobility and a higher degree of flexibility, such as for wound healing applications. Springer Netherlands 2015-01-01 2015 /pmc/articles/PMC4392120/ /pubmed/25549609 http://dx.doi.org/10.1007/s10529-014-1760-6 Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Original Research Paper
Mouthuy, Pierre-Alexis
Groszkowski, Lukasz
Ye, Hua
Performances of a portable electrospinning apparatus
title Performances of a portable electrospinning apparatus
title_full Performances of a portable electrospinning apparatus
title_fullStr Performances of a portable electrospinning apparatus
title_full_unstemmed Performances of a portable electrospinning apparatus
title_short Performances of a portable electrospinning apparatus
title_sort performances of a portable electrospinning apparatus
topic Original Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392120/
https://www.ncbi.nlm.nih.gov/pubmed/25549609
http://dx.doi.org/10.1007/s10529-014-1760-6
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