Genome Resequencing of the Virulent and Multidrug-Resistant Reference Strain Clostridium difficile 630

We resequenced the complete genome of the virulent and multidrug-resistant pathogen Clostridium difficile strain 630. A combination of single-molecule real-time and Illumina sequencing technology revealed the presence of an additional rRNA gene cluster, additional tRNAs, and the absence of a transpo...

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Autores principales: Riedel, Thomas, Bunk, Boyke, Thürmer, Andrea, Spröer, Cathrin, Brzuszkiewicz, Elzbieta, Abt, Birte, Gronow, Sabine, Liesegang, Heiko, Daniel, Rolf, Overmann, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392158/
https://www.ncbi.nlm.nih.gov/pubmed/25858846
http://dx.doi.org/10.1128/genomeA.00276-15
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author Riedel, Thomas
Bunk, Boyke
Thürmer, Andrea
Spröer, Cathrin
Brzuszkiewicz, Elzbieta
Abt, Birte
Gronow, Sabine
Liesegang, Heiko
Daniel, Rolf
Overmann, Jörg
author_facet Riedel, Thomas
Bunk, Boyke
Thürmer, Andrea
Spröer, Cathrin
Brzuszkiewicz, Elzbieta
Abt, Birte
Gronow, Sabine
Liesegang, Heiko
Daniel, Rolf
Overmann, Jörg
author_sort Riedel, Thomas
collection PubMed
description We resequenced the complete genome of the virulent and multidrug-resistant pathogen Clostridium difficile strain 630. A combination of single-molecule real-time and Illumina sequencing technology revealed the presence of an additional rRNA gene cluster, additional tRNAs, and the absence of a transposon in comparison to the published and reannotated genome sequence.
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spelling pubmed-43921582015-04-10 Genome Resequencing of the Virulent and Multidrug-Resistant Reference Strain Clostridium difficile 630 Riedel, Thomas Bunk, Boyke Thürmer, Andrea Spröer, Cathrin Brzuszkiewicz, Elzbieta Abt, Birte Gronow, Sabine Liesegang, Heiko Daniel, Rolf Overmann, Jörg Genome Announc Prokaryotes We resequenced the complete genome of the virulent and multidrug-resistant pathogen Clostridium difficile strain 630. A combination of single-molecule real-time and Illumina sequencing technology revealed the presence of an additional rRNA gene cluster, additional tRNAs, and the absence of a transposon in comparison to the published and reannotated genome sequence. American Society for Microbiology 2015-04-09 /pmc/articles/PMC4392158/ /pubmed/25858846 http://dx.doi.org/10.1128/genomeA.00276-15 Text en Copyright © 2015 Riedel et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Prokaryotes
Riedel, Thomas
Bunk, Boyke
Thürmer, Andrea
Spröer, Cathrin
Brzuszkiewicz, Elzbieta
Abt, Birte
Gronow, Sabine
Liesegang, Heiko
Daniel, Rolf
Overmann, Jörg
Genome Resequencing of the Virulent and Multidrug-Resistant Reference Strain Clostridium difficile 630
title Genome Resequencing of the Virulent and Multidrug-Resistant Reference Strain Clostridium difficile 630
title_full Genome Resequencing of the Virulent and Multidrug-Resistant Reference Strain Clostridium difficile 630
title_fullStr Genome Resequencing of the Virulent and Multidrug-Resistant Reference Strain Clostridium difficile 630
title_full_unstemmed Genome Resequencing of the Virulent and Multidrug-Resistant Reference Strain Clostridium difficile 630
title_short Genome Resequencing of the Virulent and Multidrug-Resistant Reference Strain Clostridium difficile 630
title_sort genome resequencing of the virulent and multidrug-resistant reference strain clostridium difficile 630
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392158/
https://www.ncbi.nlm.nih.gov/pubmed/25858846
http://dx.doi.org/10.1128/genomeA.00276-15
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