Expression of FcRL4 defines a pro-inflammatory, RANKL-producing B cell subset in rheumatoid arthritis

OBJECTIVES: The success of B cell targeting therapies has highlighted the importance of B cells in rheumatoid arthritis pathogenesis. We have previously shown that B cells in the RA synovium are capable of producing pro-inflammatory and bone-destructive cytokines including RANKL. Here we sought to c...

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Detalles Bibliográficos
Autores principales: Yeo, L, Lom, H, Juarez, M, Snow, M, Buckley, C D, Filer, A, Raza, K, Scheel-Toellner, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392201/
https://www.ncbi.nlm.nih.gov/pubmed/24431391
http://dx.doi.org/10.1136/annrheumdis-2013-204116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392201/
https://www.ncbi.nlm.nih.gov/pubmed/24431391
http://dx.doi.org/10.1136/annrheumdis-2013-204116

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