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Structure of a BAG6 (Bcl-2-associated Athanogene 6)-Ubl4a (Ubiquitin-like Protein 4a) Complex Reveals a Novel Binding Interface That Functions in Tail-anchored Protein Biogenesis
BAG6 is an essential protein that functions in two distinct biological pathways, ubiquitin-mediated protein degradation of defective polypeptides and tail-anchored (TA) transmembrane protein biogenesis in mammals, although its structural and functional properties remain unknown. We solved a crystal...
Autores principales: | Kuwabara, Naoyuki, Minami, Ryosuke, Yokota, Naoto, Matsumoto, Hirofumi, Senda, Toshiya, Kawahara, Hiroyuki, Kato, Ryuichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392246/ https://www.ncbi.nlm.nih.gov/pubmed/25713138 http://dx.doi.org/10.1074/jbc.M114.631804 |
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