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Actinomyces-induced inflammatory myofibroblastic tumor of the colon: A rare cause of an abdominal mass: Akbulut et al. inflammatory myofibroblastictumor due to actinomyces spp

INTRODUCTION: Inflammatory myofibroblastic tumors (IMFTs) are neoplastic lesions that are either benign or have low-grade malignancy potential. Although the etiopathogenesis is not entirely clear, many factors play a role in their development, including trauma, autoimmune disorders, and infectious a...

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Autores principales: Akbulut, Sami, Yagmur, Yusuf, Gumus, Serdar, Sogutcu, Nilgun, Demircan, Firat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392327/
https://www.ncbi.nlm.nih.gov/pubmed/25704558
http://dx.doi.org/10.1016/j.ijscr.2015.02.014
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author Akbulut, Sami
Yagmur, Yusuf
Gumus, Serdar
Sogutcu, Nilgun
Demircan, Firat
author_facet Akbulut, Sami
Yagmur, Yusuf
Gumus, Serdar
Sogutcu, Nilgun
Demircan, Firat
author_sort Akbulut, Sami
collection PubMed
description INTRODUCTION: Inflammatory myofibroblastic tumors (IMFTs) are neoplastic lesions that are either benign or have low-grade malignancy potential. Although the etiopathogenesis is not entirely clear, many factors play a role in their development, including trauma, autoimmune disorders, and infectious and inflammatory processes. However, IMFTs caused by Actinomyces spp. infection are rare, with a limited number of cases reported in the literature. PRESENTATION OF CASE: A 30-year-old woman was admitted to our clinic with abdominal pain and a palpable abdominal mass. Contrast-enhanced computed tomography revealed a tumoral lesion (11 × 10 × 7 cm) in the right colon. A right hemicolectomy and ileocolic anastomosis were performed, during which almost complete obstruction of the lumen by the 7.5 × 7.0 × 5.0 cm tumor was observed. Histopathology and immunohistochemical findings revealed that the tumor was consistent with an IMFT that developed from an Actinomyces infection. The patient was then placed on amoxicillin and doxycycline therapy. CONCLUSION: This case demonstrates that the development of IMFT secondary to actinomycosis is difficult to predict in the preoperative period. Once an exact diagnosis is confirmed by histopathologic examination, affected patients should receive prolonged antibiotherapy.
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spelling pubmed-43923272015-04-13 Actinomyces-induced inflammatory myofibroblastic tumor of the colon: A rare cause of an abdominal mass: Akbulut et al. inflammatory myofibroblastictumor due to actinomyces spp Akbulut, Sami Yagmur, Yusuf Gumus, Serdar Sogutcu, Nilgun Demircan, Firat Int J Surg Case Rep Case Report INTRODUCTION: Inflammatory myofibroblastic tumors (IMFTs) are neoplastic lesions that are either benign or have low-grade malignancy potential. Although the etiopathogenesis is not entirely clear, many factors play a role in their development, including trauma, autoimmune disorders, and infectious and inflammatory processes. However, IMFTs caused by Actinomyces spp. infection are rare, with a limited number of cases reported in the literature. PRESENTATION OF CASE: A 30-year-old woman was admitted to our clinic with abdominal pain and a palpable abdominal mass. Contrast-enhanced computed tomography revealed a tumoral lesion (11 × 10 × 7 cm) in the right colon. A right hemicolectomy and ileocolic anastomosis were performed, during which almost complete obstruction of the lumen by the 7.5 × 7.0 × 5.0 cm tumor was observed. Histopathology and immunohistochemical findings revealed that the tumor was consistent with an IMFT that developed from an Actinomyces infection. The patient was then placed on amoxicillin and doxycycline therapy. CONCLUSION: This case demonstrates that the development of IMFT secondary to actinomycosis is difficult to predict in the preoperative period. Once an exact diagnosis is confirmed by histopathologic examination, affected patients should receive prolonged antibiotherapy. Elsevier 2015-02-11 /pmc/articles/PMC4392327/ /pubmed/25704558 http://dx.doi.org/10.1016/j.ijscr.2015.02.014 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Akbulut, Sami
Yagmur, Yusuf
Gumus, Serdar
Sogutcu, Nilgun
Demircan, Firat
Actinomyces-induced inflammatory myofibroblastic tumor of the colon: A rare cause of an abdominal mass: Akbulut et al. inflammatory myofibroblastictumor due to actinomyces spp
title Actinomyces-induced inflammatory myofibroblastic tumor of the colon: A rare cause of an abdominal mass: Akbulut et al. inflammatory myofibroblastictumor due to actinomyces spp
title_full Actinomyces-induced inflammatory myofibroblastic tumor of the colon: A rare cause of an abdominal mass: Akbulut et al. inflammatory myofibroblastictumor due to actinomyces spp
title_fullStr Actinomyces-induced inflammatory myofibroblastic tumor of the colon: A rare cause of an abdominal mass: Akbulut et al. inflammatory myofibroblastictumor due to actinomyces spp
title_full_unstemmed Actinomyces-induced inflammatory myofibroblastic tumor of the colon: A rare cause of an abdominal mass: Akbulut et al. inflammatory myofibroblastictumor due to actinomyces spp
title_short Actinomyces-induced inflammatory myofibroblastic tumor of the colon: A rare cause of an abdominal mass: Akbulut et al. inflammatory myofibroblastictumor due to actinomyces spp
title_sort actinomyces-induced inflammatory myofibroblastic tumor of the colon: a rare cause of an abdominal mass: akbulut et al. inflammatory myofibroblastictumor due to actinomyces spp
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392327/
https://www.ncbi.nlm.nih.gov/pubmed/25704558
http://dx.doi.org/10.1016/j.ijscr.2015.02.014
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