Cargando…

Anaplastic carcinoma in submandibular region: A diagnostic dilemma

INTRODUCTION: Thyroid carcinoma arising in an extrathyroid area is a rare entity. PRESENTATION OF CASE: We report a case of anaplastic carcinoma in the submandibular region occurring in a 70-year-old woman. DISCUSSION: The location of the mass along with no evidence of primary tumor at the orthotopi...

Descripción completa

Detalles Bibliográficos
Autores principales: Koltsidopoulos, Petros, Sioka, Eleni, Fericean, Antzela, Zacharoulis, Dimitrios, Skoulakis, Charalambos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392330/
https://www.ncbi.nlm.nih.gov/pubmed/25697543
http://dx.doi.org/10.1016/j.ijscr.2015.02.015
_version_ 1782365960841199616
author Koltsidopoulos, Petros
Sioka, Eleni
Fericean, Antzela
Zacharoulis, Dimitrios
Skoulakis, Charalambos
author_facet Koltsidopoulos, Petros
Sioka, Eleni
Fericean, Antzela
Zacharoulis, Dimitrios
Skoulakis, Charalambos
author_sort Koltsidopoulos, Petros
collection PubMed
description INTRODUCTION: Thyroid carcinoma arising in an extrathyroid area is a rare entity. PRESENTATION OF CASE: We report a case of anaplastic carcinoma in the submandibular region occurring in a 70-year-old woman. DISCUSSION: The location of the mass along with no evidence of primary tumor at the orthotopic thyroid gland posed a diagnostic dilemma: was this an ectopic thyroid carcinoma or rather a case of occult differentiated thyroid carcinoma metastasis that transformed to anaplastic carcinoma? Based on the histopathological findings we concluded that the tumor arised in ectopic thyroid tissue. Although the mass was completely resected, the patient died 10 months after diagnosis due to pulmonary metastases. CONCLUSION: Conclusively, the possibility of ectopic thyroid tissue, with or without disease, should be considered in cases of a mass in the submandibular region.
format Online
Article
Text
id pubmed-4392330
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-43923302015-04-13 Anaplastic carcinoma in submandibular region: A diagnostic dilemma Koltsidopoulos, Petros Sioka, Eleni Fericean, Antzela Zacharoulis, Dimitrios Skoulakis, Charalambos Int J Surg Case Rep Case Report INTRODUCTION: Thyroid carcinoma arising in an extrathyroid area is a rare entity. PRESENTATION OF CASE: We report a case of anaplastic carcinoma in the submandibular region occurring in a 70-year-old woman. DISCUSSION: The location of the mass along with no evidence of primary tumor at the orthotopic thyroid gland posed a diagnostic dilemma: was this an ectopic thyroid carcinoma or rather a case of occult differentiated thyroid carcinoma metastasis that transformed to anaplastic carcinoma? Based on the histopathological findings we concluded that the tumor arised in ectopic thyroid tissue. Although the mass was completely resected, the patient died 10 months after diagnosis due to pulmonary metastases. CONCLUSION: Conclusively, the possibility of ectopic thyroid tissue, with or without disease, should be considered in cases of a mass in the submandibular region. Elsevier 2015-02-11 /pmc/articles/PMC4392330/ /pubmed/25697543 http://dx.doi.org/10.1016/j.ijscr.2015.02.015 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Koltsidopoulos, Petros
Sioka, Eleni
Fericean, Antzela
Zacharoulis, Dimitrios
Skoulakis, Charalambos
Anaplastic carcinoma in submandibular region: A diagnostic dilemma
title Anaplastic carcinoma in submandibular region: A diagnostic dilemma
title_full Anaplastic carcinoma in submandibular region: A diagnostic dilemma
title_fullStr Anaplastic carcinoma in submandibular region: A diagnostic dilemma
title_full_unstemmed Anaplastic carcinoma in submandibular region: A diagnostic dilemma
title_short Anaplastic carcinoma in submandibular region: A diagnostic dilemma
title_sort anaplastic carcinoma in submandibular region: a diagnostic dilemma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392330/
https://www.ncbi.nlm.nih.gov/pubmed/25697543
http://dx.doi.org/10.1016/j.ijscr.2015.02.015
work_keys_str_mv AT koltsidopoulospetros anaplasticcarcinomainsubmandibularregionadiagnosticdilemma
AT siokaeleni anaplasticcarcinomainsubmandibularregionadiagnosticdilemma
AT fericeanantzela anaplasticcarcinomainsubmandibularregionadiagnosticdilemma
AT zacharoulisdimitrios anaplasticcarcinomainsubmandibularregionadiagnosticdilemma
AT skoulakischaralambos anaplasticcarcinomainsubmandibularregionadiagnosticdilemma