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Malignant phyllodes tumour presenting as a massive fungating breast mass and silent thrombo-embolism

INTRODUCTION: We report an unusual case of a massive malignant phyllodes tumour that had almost replaced the entire breast presenting with severe chronic blood loss, extensive deep venous thrombosis (DVT) and a silent pulmonary embolus. PRESENTATION: Long-standing neglected massive fungating ulcerat...

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Autores principales: Bourke, Anita G., McCreanor, Madeleine, Yeo, Allen, Weber, Dieter, Bartlett, Anthony, Backhouse, Anastasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392335/
https://www.ncbi.nlm.nih.gov/pubmed/25734318
http://dx.doi.org/10.1016/j.ijscr.2015.02.032
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author Bourke, Anita G.
McCreanor, Madeleine
Yeo, Allen
Weber, Dieter
Bartlett, Anthony
Backhouse, Anastasia
author_facet Bourke, Anita G.
McCreanor, Madeleine
Yeo, Allen
Weber, Dieter
Bartlett, Anthony
Backhouse, Anastasia
author_sort Bourke, Anita G.
collection PubMed
description INTRODUCTION: We report an unusual case of a massive malignant phyllodes tumour that had almost replaced the entire breast presenting with severe chronic blood loss, extensive deep venous thrombosis (DVT) and a silent pulmonary embolus. PRESENTATION: Long-standing neglected massive fungating ulcerative mass larger than the left haemothorax. DISCUSSION: Phyllodes tumours are rare fibro-epithelial breast lesions that have the propensity to grow rapidly to a large size if neglected. Larger tumours are more likely to be malignant with an overall metastatic rate around 10%. An incidental pulmonary embolus arising from extensive silent lower limb deep vein thrombosis requiring an IVC filter complicated the surgical management. CONCLUSION: Phyllodes tumours are rare and account for approximately 0.3–0.5% of all breast tumours [1]. They have the propensity to be fast growing. However, tumours reaching a massive size (>10 cm) are rare with few reports in the literature.
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spelling pubmed-43923352015-04-13 Malignant phyllodes tumour presenting as a massive fungating breast mass and silent thrombo-embolism Bourke, Anita G. McCreanor, Madeleine Yeo, Allen Weber, Dieter Bartlett, Anthony Backhouse, Anastasia Int J Surg Case Rep Case Report INTRODUCTION: We report an unusual case of a massive malignant phyllodes tumour that had almost replaced the entire breast presenting with severe chronic blood loss, extensive deep venous thrombosis (DVT) and a silent pulmonary embolus. PRESENTATION: Long-standing neglected massive fungating ulcerative mass larger than the left haemothorax. DISCUSSION: Phyllodes tumours are rare fibro-epithelial breast lesions that have the propensity to grow rapidly to a large size if neglected. Larger tumours are more likely to be malignant with an overall metastatic rate around 10%. An incidental pulmonary embolus arising from extensive silent lower limb deep vein thrombosis requiring an IVC filter complicated the surgical management. CONCLUSION: Phyllodes tumours are rare and account for approximately 0.3–0.5% of all breast tumours [1]. They have the propensity to be fast growing. However, tumours reaching a massive size (>10 cm) are rare with few reports in the literature. Elsevier 2015-02-19 /pmc/articles/PMC4392335/ /pubmed/25734318 http://dx.doi.org/10.1016/j.ijscr.2015.02.032 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Bourke, Anita G.
McCreanor, Madeleine
Yeo, Allen
Weber, Dieter
Bartlett, Anthony
Backhouse, Anastasia
Malignant phyllodes tumour presenting as a massive fungating breast mass and silent thrombo-embolism
title Malignant phyllodes tumour presenting as a massive fungating breast mass and silent thrombo-embolism
title_full Malignant phyllodes tumour presenting as a massive fungating breast mass and silent thrombo-embolism
title_fullStr Malignant phyllodes tumour presenting as a massive fungating breast mass and silent thrombo-embolism
title_full_unstemmed Malignant phyllodes tumour presenting as a massive fungating breast mass and silent thrombo-embolism
title_short Malignant phyllodes tumour presenting as a massive fungating breast mass and silent thrombo-embolism
title_sort malignant phyllodes tumour presenting as a massive fungating breast mass and silent thrombo-embolism
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392335/
https://www.ncbi.nlm.nih.gov/pubmed/25734318
http://dx.doi.org/10.1016/j.ijscr.2015.02.032
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