MiR-377 targets E2F3 and alters the NF-kB signaling pathway through MAP3K7 in malignant melanoma

BACKGROUND: The incidence of cutaneous malignant melanoma continues to rise, and once the disease metastasizes it is almost inevitably fatal. We recently reported that a large miRNAs cluster on human chromosome 14q32, implicated in many types of cancers, is significantly down-regulated in melanoma....

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Detalles Bibliográficos
Autores principales: Zehavi, Liron, Schayek, Hagit, Jacob-Hirsch, Jasmine, Sidi, Yechezkel, Leibowitz-Amit, Raya, Avni, Dror
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392476/
https://www.ncbi.nlm.nih.gov/pubmed/25889255
http://dx.doi.org/10.1186/s12943-015-0338-9

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