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Endovascular and microsurgical treatment of cerebral arteriovenous malformations: Current recommendations

BACKGROUND: Cerebral arteriovenous malformations (AVMs) can be a heterogeneous pathological entity whose management requires a complex decision-making process due to the risks associated with their treatment and natural history. Despite the recently published conclusions of the aborted Randomized Tr...

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Detalles Bibliográficos
Autores principales: Conger, Andrew, Kulwin, Charles, Lawton, Michael T., Cohen-Gadol, Aaron A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392538/
https://www.ncbi.nlm.nih.gov/pubmed/25883831
http://dx.doi.org/10.4103/2152-7806.153707
Descripción
Sumario:BACKGROUND: Cerebral arteriovenous malformations (AVMs) can be a heterogeneous pathological entity whose management requires a complex decision-making process due to the risks associated with their treatment and natural history. Despite the recently published conclusions of the aborted Randomized Trial of Brain Unruptured AVMs (ARUBA) trial, the authors of this article believe multimodality intervention in general and microsurgical resection in particular continue to play a major role in the management of carefully selected ruptured or unruptured AVMs. METHODS: The authors provide an overview of their methodology for endovascular intervention and microsurgical resection and share their technical nuances for successful embolization and microsurgical resection of AVMs with special emphasis on complication avoidance. RESULTS: The authors have achieved successful outcomes in embolization and resection of cerebral AVMs when using their methodology. CONCLUSIONS: These lesions are among the most technically difficult pathological entities handled by the cerebrovascular specialist, and an overview of technical concepts to help systematize this challenging and variable endeavor can improve the safety of their treatment.