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Endovascular and microsurgical treatment of cerebral arteriovenous malformations: Current recommendations

BACKGROUND: Cerebral arteriovenous malformations (AVMs) can be a heterogeneous pathological entity whose management requires a complex decision-making process due to the risks associated with their treatment and natural history. Despite the recently published conclusions of the aborted Randomized Tr...

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Autores principales: Conger, Andrew, Kulwin, Charles, Lawton, Michael T., Cohen-Gadol, Aaron A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392538/
https://www.ncbi.nlm.nih.gov/pubmed/25883831
http://dx.doi.org/10.4103/2152-7806.153707
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author Conger, Andrew
Kulwin, Charles
Lawton, Michael T.
Cohen-Gadol, Aaron A.
author_facet Conger, Andrew
Kulwin, Charles
Lawton, Michael T.
Cohen-Gadol, Aaron A.
author_sort Conger, Andrew
collection PubMed
description BACKGROUND: Cerebral arteriovenous malformations (AVMs) can be a heterogeneous pathological entity whose management requires a complex decision-making process due to the risks associated with their treatment and natural history. Despite the recently published conclusions of the aborted Randomized Trial of Brain Unruptured AVMs (ARUBA) trial, the authors of this article believe multimodality intervention in general and microsurgical resection in particular continue to play a major role in the management of carefully selected ruptured or unruptured AVMs. METHODS: The authors provide an overview of their methodology for endovascular intervention and microsurgical resection and share their technical nuances for successful embolization and microsurgical resection of AVMs with special emphasis on complication avoidance. RESULTS: The authors have achieved successful outcomes in embolization and resection of cerebral AVMs when using their methodology. CONCLUSIONS: These lesions are among the most technically difficult pathological entities handled by the cerebrovascular specialist, and an overview of technical concepts to help systematize this challenging and variable endeavor can improve the safety of their treatment.
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spelling pubmed-43925382015-04-16 Endovascular and microsurgical treatment of cerebral arteriovenous malformations: Current recommendations Conger, Andrew Kulwin, Charles Lawton, Michael T. Cohen-Gadol, Aaron A. Surg Neurol Int Original Article BACKGROUND: Cerebral arteriovenous malformations (AVMs) can be a heterogeneous pathological entity whose management requires a complex decision-making process due to the risks associated with their treatment and natural history. Despite the recently published conclusions of the aborted Randomized Trial of Brain Unruptured AVMs (ARUBA) trial, the authors of this article believe multimodality intervention in general and microsurgical resection in particular continue to play a major role in the management of carefully selected ruptured or unruptured AVMs. METHODS: The authors provide an overview of their methodology for endovascular intervention and microsurgical resection and share their technical nuances for successful embolization and microsurgical resection of AVMs with special emphasis on complication avoidance. RESULTS: The authors have achieved successful outcomes in embolization and resection of cerebral AVMs when using their methodology. CONCLUSIONS: These lesions are among the most technically difficult pathological entities handled by the cerebrovascular specialist, and an overview of technical concepts to help systematize this challenging and variable endeavor can improve the safety of their treatment. Medknow Publications & Media Pvt Ltd 2015-03-19 /pmc/articles/PMC4392538/ /pubmed/25883831 http://dx.doi.org/10.4103/2152-7806.153707 Text en Copyright: © 2015 Conger A. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Original Article
Conger, Andrew
Kulwin, Charles
Lawton, Michael T.
Cohen-Gadol, Aaron A.
Endovascular and microsurgical treatment of cerebral arteriovenous malformations: Current recommendations
title Endovascular and microsurgical treatment of cerebral arteriovenous malformations: Current recommendations
title_full Endovascular and microsurgical treatment of cerebral arteriovenous malformations: Current recommendations
title_fullStr Endovascular and microsurgical treatment of cerebral arteriovenous malformations: Current recommendations
title_full_unstemmed Endovascular and microsurgical treatment of cerebral arteriovenous malformations: Current recommendations
title_short Endovascular and microsurgical treatment of cerebral arteriovenous malformations: Current recommendations
title_sort endovascular and microsurgical treatment of cerebral arteriovenous malformations: current recommendations
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392538/
https://www.ncbi.nlm.nih.gov/pubmed/25883831
http://dx.doi.org/10.4103/2152-7806.153707
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