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Brg1 modulates enhancer activation in mesoderm lineage commitment

The interplay between different levels of gene regulation in modulating developmental transcriptional programs, such as histone modifications and chromatin remodeling, is not well understood. Here, we show that the chromatin remodeling factor Brg1 is required for enhancer activation in mesoderm indu...

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Detalles Bibliográficos
Autores principales: Alexander, Jeffrey M., Hota, Swetansu K., He, Daniel, Thomas, Sean, Ho, Lena, Pennacchio, Len A., Bruneau, Benoit G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392595/
https://www.ncbi.nlm.nih.gov/pubmed/25813539
http://dx.doi.org/10.1242/dev.109496